JH-II-127

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LRRK2 inhibitor

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Catalog No. A15777

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
JH-II-127 5mg A15777-5

Regular Price: $120.00

Special Price: $96.00

JH-II-127 10mg A15777-10

Regular Price: $200.00

Special Price: $160.00

JH-II-127 25mg A15777-25

Regular Price: $400.00

Special Price: $320.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

JH-II-127 is a highly potent, selective, and brain penetrant LRRK2 inhibitor, with IC50 of 6.6 nM, 2.2 nM ,47.7 nM for LRRK2-wild-type, LRRK2-G2019S, LRRK2-A2016T.

JH-II-127

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Chemical Information

Catalog Num A15777
Actions Inhibitor
M. Wt 416.86
Formula C19H21ClN6O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1700693-08-8
Synonyms N/A
SMILES code CNC1=NC(=NC2=C1C(=CN2)Cl)NC3=C(C=C(C=C3)C(=O)N4CCOCC4)OC
Chemical Name N/A

Biological Activity

Description
JH-II-127 is a highly potent, selective, and brain penetrant LRRK2 inhibitor, with IC50 of 6.6 nM, 2.2 nM ,47.7 nM for LRRK2-wild-type, LRRK2-G2019S, LRRK2-A2016T.

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