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Lipoxygenase



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Catalog No. Product Name Application Product Information
A11725 SALE

Edaravone (MCI-186)

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Edaravone is a free radical scavenger with diverse protective effects that inhibits production of reactive oxygen species, apoptosis and the lipoxygenase system.
A12879

Tepoxalin

COX/5-LOX inhibitor
Tepoxalin is a dual cyclooxygenase/5-lipoxygenase inhibitor of arachidonic acid metabolism with potent anti-inflammatory activity and a favorable gastrointestinal profile
A12061

Ginkgetin

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Ginkgetin, a Biflavone from Ginko biloba leaves, inhibits cyclooxygenases-2 and 5-lipoxygenase in mouse bone marrow-derived mast cells.
A14994

AM679

FLAP inhibitor
AM679 is a potent and selective FLAP inhibitor with IC50s of 2.2 nM/0.6 nM/154 nM for FLAP binding/hLA/hWB respectively.
A15190

Nordihydroguaiaretic acid

lipoxygenase inhibitor
Nordihydroguaiaretic acid is a natural phenolic compound isolated from the creosote bush Larrea divaricata, which has anti-tumor activities both in vitro and in vivo. Its analogs are in clinical development for use in refractory solid tumors.
A15169

MK591

FLAP inhibitor
MK591 is selective and specific inhibitor of 5-Lipoxygenase-activating protein (FLAP).
A15163

MK-0591 (Quiflapon)

FLAP inhibitor
MK-0591 is a selective and specific 5-Lipoxygenase-activating protein (FLAP) inhibitor with an IC50 value of 1.6 nM in a FLAP binding assay.
A14553

6,7-Dihydroxycoumarin

5-lipoxygenase inhibitor
Esculetin, a phenolic compound, acts as a 5-LO (5-lipoxygenase, 5-LOX) inhibitor.
A14400

AZD6642

FLAP inhibitor
AZD6642 is an inhibitor of 5-Lipoxygenase Activating Protein (FLAP) for the treatment of inflammatory diseases.
A13346

MK 886

leukotriene biosynthesis inhibitor
MK-886 is an inhibitor of leukotriene biosynthesis (IC50 = 3 nM in human polymorphonuclear leukocytes).
A15818

GSK2190915

FLAP inhibitor
GSK2190915 is a potent FLAP(5-Lipoxygenase-activating protein) inhibitor with binding IC50 of 2.9 nM.

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