LY2835219 (abemaciclib)

LY2835219 is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity.
Grouped product items
Product Name Price Stock Qty
LY2835219 5mg
$60.00
In stock
LY2835219 10mg
$90.00
In stock
LY2835219 50mg
$110.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Not your Region? View all Distributors

Adooq Products cited in reputable paper
Adooq's LY2835219 (abemaciclib) has been cited by 8 publications
  • Elaheh S Abutorabi, .et al. , Mol Biol Rep, 2023, May;50(5):4073-4082 PMID: 36877344
  • Yoshinori Tanaka, .et al. , Biochem Biophys Res Commun, 2022, Jul 23;614:191-97 PMID: 35598430
  • Sumire Suzuki, .et al. , Oncol Rep, 2022, Feb;47(2):40 PMID: 34958115
  • Kana Nakatani, .et al. , Int J Hematol, 2020, Oct 17 PMID: 33068248
  • Ryohei Ogata, .et al. , Breast Cancer, 2020, Aug 28 PMID: 32860163
  • Elaheh Seyed Abutorabi, .et al. , Rep Biochem Mol Biol, 2020, Jan; 8(4): 438-445 PMID: 32582803
  • Hidemasa Matsuo, .et al. , Blood Adv, 2018, Nov 13; 2(21): 2879-2889 PMID: 30381403
  • Iriyama N, .et al. , Leuk Lymphoma, 2018, Jun;59(6):1439-1450 PMID: 28918692
  • Biological Activity
    Discription LY2835219 is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity.
    Targets
    Target Value
    Product Information
    Catalog Num A12989
    Formula C27H32F2N8
    Molecular Weight 506.59
    CAS Number 1231929-97-7
    SMILES CCN1CCN(CC1)CC2=CN=C(C=C2)NC3=NC=C(C(=N3)C4=CC5=C(C(=C4)F)N=C(N5C(C)C)C)F
    Synonyms LY 2835219, LY-2835219
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 6 mg/mL (11.84 mM)
    Water Insoluble
    Ethanol 8 mg/mL (15.79 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 19.74 mL 98.7 mL 197.4 mL
    0.5 mM 3.95 mL 19.74 mL 39.48 mL
    1 mM 1.97 mL 9.87 mL 19.74 mL
    5 mM 0.39 mL 1.97 mL 3.95 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
    Keywords: buy LY2835219 (abemaciclib) | LY2835219 (abemaciclib) Supplier | purchase LY2835219 (abemaciclib) | LY2835219 (abemaciclib) cost | LY2835219 (abemaciclib) manufacturer | order LY2835219 (abemaciclib) | LY2835219 (abemaciclib) distributor | buy 1231929-97-7 | 1231929-97-7 Supplier | purchase 1231929-97-7 | 1231929-97-7 cost | 1231929-97-7 manufacturer | order 1231929-97-7 | 1231929-97-7 distributor