HCV Protease

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  1. HCV nucleotide inhibitor

    PSI-352938 (PSI-938) is a hepatitis C virus (HCV) nucleotide inhibitor.
  2. HCV NS5B RNA-dependent RNA polymerase inhibitor

    Beclabuvir is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, and inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 with IC50 of < 28 nM.
  3. HCV RNA replication inhibitor

    PSI-7976 is the isomer of PSI-7977. PSI-7977 is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity.
  4. HCV RNA replication inhibitor

    Sofosbuvir impurity C is the less active impurity of Sofosbuvir, Sofosbuvir is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity.
  5. HCV RNA replication inhibitor

    Sofosbuvir impurity A, an diastereoisomer of sofosbuvir, is the impurity of sofosbuvir. Sofosbuvir (PSI-7977) is an inhibitor of HCV RNA replication, demonstrates potent anti-hepatitis C virus activity.
  6. HCV NS5B polymerase inhibitor

    NM107 (2'-C-Methylcytidine) is an nucleoside inhibitor of the hepatitis C virus (HCV) NS5B polymerase, the EC50 of NM107 in the wild-type replicon cells is 1.85 μM.
  7. HCV NS5B polymerase inhibitor

    PSI-6206 13CD3 is the deuterium labeled PSI-6206. PSI-6206 is the deaminated derivative of PSI-6130, which is a potent and selective inhibitor of HCV NS5B polymerase.
  8. cyclophilin inhibitor

    Alisporivir (DEB-025; Debio-025) is a cyclophilin inhibitor molecule with potent anti-hepatitis C virus (HCV) activity.
  9. inhibitor of hepatitis C virus (HCV)

    HZ-1157 is an inhibitor of hepatitis C virus (HCV) with inhibitory activities toward HCV NS3/4A protease.
  10. HCV NS5A inhibitor

    Pibrentasvir, also known as ABT-530, is a protease inhibitor potentially for the treatment of HCV infection.
  11. type 1 (SR-BI) inhibitor

    BLT-1, a thiosemicarbazone copper chelator, is a selective scavenger receptor B, type 1 (SR-BI) inhibitor. BLT-1 inhibits the transfer of lipids between high-density lipoproteins (HDL) and cells mediated by SR-BI. BLT-1 is a potent HCV entry inhibitor.

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