Others

Silymarin (Silibinin B) inhibits chemically induced urinary bladder tumor growth and progression possibly by inhibiting cell proliferation and enhancing apoptosis.

Sinomenine(Cucoline) is traditionally used in herbal medicine in these countries, as a treatment for rheumatism and arthritis.

Sophocarpine could reverse isoprenaline-induced arrhythmia and inhibit I(Na), I(CaL), and I(Kr) currents. The electrophysiological effects of sophocarpine are similar to those of amiodarone, which might be regarded as a prospective antiarrhythmic agent.

Spectinomycin is an antibiotic useful for the treatment of the bacterial infection, gonorrhea.

Stigmasterol, which is readily obtainable from soybean oil, can be transformed easily to progesterone and to other hormones.

Streptozotocin (Streptozocin, Zanosar, STZ)is used in medical research to produce an animal model for Type 1 diabetes, which directly inhibist the O-GlcNAcase activity of the enzyme NCOAT in vitro.

Cilastatin is a dipeptidase inhibitor that specifically inhibits DPEP1 (dehydrodipeptidase I), a renal membrane-bound glycoprotein involved in the hydrolytic metabolism of penem and carbapenem ??-lactam antibiotics.

Tangeretin (Tangeritin) is an O-polymethoxylated flavone that is found in tangerine and other citrus peels. Tangeretin (Tangeritin) strengthens the cell wall and acts as a plant's defensive mechanism against disease-causing pathogens. Tangeretin (Tangeritin) also shows enormous potential as an anti cancer agent.

Taurine is an organic acid widely distributed in animal tissues. It is a major constituent of bile and can be found in the large intestine and accounts for approximately 0.1% of total human body weight.

Isoindigotin is a potential antileukemic agent.

Tenoxicam belongs to the class of NSAIDs known as oxicams.

Terbinafine HCl a member of the allylamine class of antifungals, has been found to be a specific inhibitor of ergosterol synthesis via squalene epoxidase inhibition.

Indacaterol is an ultra-long-acting beta-adrenoceptor agonist.

Theobromine(3,7-Dimethylxanthine) is a xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than theophylline and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension.

Tranilast is an antiallergic drug. It reduces collagen synthesis in fibroblasts and inhibits growth of neurofibroma cells, also inhibits the production of interleukin-6 in endothelial cells.

Troxerutin(Trihydroxyethylrutin) is a flavonol, a type of flavonoid. It is more accurately a hydroxyethylrutoside. It can be isolated from Sophora japonica, the japanese pagoda tree.It is used as a vasoprotective.

Ursolic acid(Malol) is a pentacyclic triterpene acid, used in cosmetics, that is also capable of inhibiting various types of cancer cells by inhibiting the STAT3 activation pathway and human fibrosarcoma cells by reducing the expression of matrix metalloproteinase-9 by acting through the glucocorticoid receptor.

Vanillylacetone is similar in chemical structure to other flavor chemicals such as vanillin and eugenol. It is used as a flavor additive in spice oils and in perfumery to introduce spicy aromas.

Xanthone is an organic compound. It can be prepared by the heating of phenyl salicylate. In 1939, xanthone was introduced as an insecticide and it currently finds uses as ovicide for codling moth eggs and as a larvicide. Xanthone is also used in the preparation of xanthydrol, which is used in the determination of urea levels in the blood

Yohimbine hydrochloride (Antagonil) is a α2-adrenoceptor antagonist (pKi values are 8.52, 8.00 and 9.17 for human α2A, α2B and α2C receptors respectively)

Nitrisinone is a competitive inhibitor that reversibly inhibits 4-Hydroxyphenylpyruvate oxidase (dioxygenase).

BAPTA is a selective calcium chelator.

Folinic Acid Calcium Salt (Leucovorin) is the active form of the B complex vitamin Folate is used as an antidote to cancer treatment drugs (i.e. methotrexate) to reduce toxicity of residual drugs.

Laquinimod (ABR-215062) is a potent immunomodulator.

Ribitol is a crystalline pentose alcohol formed by the reduction of ribose.

Chaetominine, a cytotoxic alkaloid produced by endophytic Chaetomium sp. IFB-E015.

QS-11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor.

Troxacitabine is a nucleoside analogue with anticancer activity. Its use is being studied in patients with refractory lymphoproliferative diseases.

P005672 is a phase II drug for antibacterial/anti-inflammatory acne treatment.

Cefozopran is a fourth-generation cephalosporin. It would be effective against respiratory tract, urinary tract, and soft tissue infections caused by a variety of gram-positive and gram-negative bacteria in humans.

Azafen is a tricyclic antidepressant.It acts as a potent inhibitor of the reuptake of serotonin.

Besifloxacin is a fourth-generation fluoroquinolone antibiotic.

Calcipotriol hydrate is the hydrate form of vitamin D3 that displays minimal effects on calcium homeostasis.

CB 300919 is a potential therapy for ovarian cancer. Preclinical data showed that this quinazoline-based compound CB 300919 has a continuous exposure (96 h) growth inhibition IC50 value of 2 nM in human CH1 ovarian tumor xenograft

Caspofungin is a semi-synthetic analogue of pneumocandin B0 with improved water solubility, a significant limitation in the development of the echinocandin class as pharmaceuticals.

Cot inhibitor-1 is a COT/Tpl2 inhibitor.

Collagen proline hydroxylase inhibitor-1 is an antifibroproliferative agents.

Chondroitin sulfate is a sulfated glycosaminoglycan (GAG) composed of a chain of alternating sugars.

LY2608204 is a potent used to treat type 2 diabetes. In a clinical trial, a study was performed to evaluate the safety and tolerability of LY2608204 in patients with type 2 diabetes.

D-Fagomine is an iminosugar originally isolated from seeds of buckwheat (Fagopyrum sculentum Moench)

Glyoxalase I inhibitor is a potent Glyoxalase I inhibitor, candidate for anticancer agents.

BD-AcAc 2, added in diet, could elevated mean blood ketone bodies of 3.5 mm and lowered plasma glucose, insulin, and leptin in animals; ketone ester given orally would delay CNS-OT seizures in rats breathing hyperbaric oxygen.

Ko 143 is potent and selective inhibitor of breast cancer resistance protein multidrug transporter (BCRP) with an EC90 value of 26 nM.

Rocuronium (Org-9426) is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia.

Salmefamol is useful for treatment of respiratory diseases

Tedizolid (TR-701) is a novel oxazolidinone antibacterial agent.

Zanamivir is a neuraminidase inhibitor used in the treatment and prophylaxis of influenza caused by influenza A virus and influenza B virus.

Cephalomannine is an active anti-cancer agent obtained from Taxus yunnanensis and has an antineoplastic effect on tumors found in mice.

Clindamycin palmitate HCl is a water soluble hydrochloride salt of the ester of clindamycin and palmitic acid and a lincosamide antibiotic.