PERK

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  1. Inhibitor (3)


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Catalog No. Product Name Application Product Information
A12792

GSK2606414

PERK inhibitor
GSK2606414 is an orally available, potent, and selective PERK inhibitor.
A13577

GSK2656157

PERK Inhibitor II
GSK2656157 is an ATP-competitive inhibitor of PERK enzyme activity with an IC(50) of 0.9 nmol/L. It is highly selective for PERK with IC(50) values >100 nmol/L against a panel of 300 kinases.
A13816

ISRIB (trans-isomer)

PERK inhibitor
ISRIB (trans-isomer) is a potent and selective small molecule inhibitor of PERK signaling (IC50 ~5 nM) that can potently reverse the effects of eIF2α phosphorylation.

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