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Pexidartinib (PLX3397)


CSF1/Kit/FLT3 inhibitor

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Catalog No. A15520

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Pexidartinib 10mg A15520-10

Regular Price: $75.00

Special Price: $60.00

Pexidartinib 25mg A15520-25

Regular Price: $150.00

Special Price: $120.00

Pexidartinib 50mg A15520-50

Regular Price: $240.00

Special Price: $192.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Pexidartinib is a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential antineoplastic activity.

Pexidartinib (PLX3397)

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Chemical Information

Catalog Num A15520
Actions Inhibitor
M. Wt 417.81
Formula C20H15ClF3N5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1029044-16-3
Synonyms PLX-3397, PLX 3397
SMILES code FC(C1=CC=C(CNC2=NC=C(CC3=CNC4=NC=C(Cl)C=C43)C=C2)C=N1)(F)F
Chemical Name N-[5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-2-pyridinyl]-6-(trifluoromethyl)-3-pyridinemethanamine

Biological Activity

Pexidartinib is a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential antineoplastic activity.
Kit CSF-1R Flt3
10 nM20 nM160 nM

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