Phosphatase



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Catalog No. Product Name Application Product Information
A10854 SALE

Sodium orthovanadate

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Sodium orthovanadate is the chemical compound Na3VO4. It is an inhibitor of protein tyrosine phosphatases, alkaline phosphatases and a number of ATPases, most likely acting as a phosphate analogue.
A13049

Tautomycetin

PP1 inhibitor
Tautomycetin induces apoptosis by inactivating Akt through a PP1-independent signaling pathway in human breast cancer cells.
A12791

Sephin1

PPP1R15A inhibitor
Sephin1 is a selective inhibitor of stress-induced PPP1R15A and targets disease associated with accumulation of misfolded protein.
A11597

LB-100

PP2A inhibitor
LB-100 is a small-molecular protein phosphatase 2A(PP2A)inhibitor with IC50 of 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells.
A11470

NSC 95397

Phosphatase inhibitor
NSC 95397 is a selective and effective dual-specificity, quinone-based phosphatase inhibitor.
A15434

Cyclosporine

Calcineurin inhibitor
Cyclosporine is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation.
A15384

NSC 87877

SHP1/2 PTPase Inhibitor
NSC 87877 is a potent inhibitor of shp2 and shp1 protein tyrosine phosphatases (SH-PTP2 and SH-PTP1).
A15383

BVT 948

PTP inhibitor
BVT 948 is a non-competitive PTP (protein tyrosine phosphatase) inhibitor.
A15382

Alexidine dihydrochloride

PTPMT1 inhibitor
Alexidine is an alkyl bis(biguanide) antiseptic which has been used in mouthwashes to eliminate plaque forming microorganisms.
A15379

Fumonisin B1

serine/threonine phosphatase inhibitor
Fumonisin B1 is a fungal metabolite produced by Fusarium moniliforme, that has been shown to inhibit protein serine/threonine phosphatases (PP1, PP2A, PP2B, PP2C, and PP5/T/K/H), and is most effective with PP5.
A15377

Ceramide

Ser/Thr protein phosphatase activator
Ceramide is a ceramide shown to be a potent modulator of proliferation and differentiation, used as a tool for studying the complex signaling associated with the ceramides.
A15376

Calcineurin Autoinhibitory Peptide

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Calcineurin inhibitory peptide is a selective inhibitor of Ca2+-calmodulin-dependent protein phosphatase (calcineurin) (IC50 ~ 10 uM). Does not inhibit PP1, PP2A or CaM kinase II (IC50 > 100 mM).
A14310

Microcystin-LR

protein phosphatase inhibitor
Microcystin-LR is a potent protein phosphatase inhibitor with IC50 of 0.04 nM for PP2A, >40-fold selectivity over PP1.
A14305 SALE

Sal003

eIF2α phosphatase inhibitor
Sal003 is a potent and cell-permeable eIF-2α phosphatase inhibitor.
A14289 SALE

CCT007093

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CCT007093 is a potent PPM1D (WIP1) inhibitor with IC50 of 8.4 μM.
A14271

(-)-p-Bromotetramisole Oxalate

phosphatase inhibitor
(-)-p-Bromotetramisole Oxalate is a potent and non-specific alkaline phosphatase inhibitor.
A16120

NSC87877

SHP inhibitor
NSC-87877 is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively.

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