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PNRI-299

AP-1 transcription inhibitor

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Catalog No. A16305

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
PNRI-299 5mg A16305-5
$320.00
PNRI-299 10mg A16305-10
$480.00
PNRI-299 50mg A16305-50
$1,400.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

PNRI-299 is a selective AP-1 transcription inhibitor with IC50 of 20 uM without affecting NF-kappaB transcription (up to 200 μM) or thioredoxin (up to 200 μM).

PNRI-299

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Chemical Information

Catalog Num A16305
Actions Inhibitor
M. Wt 401.37
Formula C21H15N5O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 550368-41-7
Synonyms PNRI299, PNRI 299
SMILES code C1C(=O)C=C(N2N1C(=O)N(C2=O)C3=CC=CC(=C3)C#N)C(=O)NCC4=CC=CC=C4
Chemical Name N-benzyl-2-(3-cyanophenyl)-1,3,6-trioxo-5H-[1,2,4]triazolo[1,2-a]pyridazine-8-carboxamide

Biological Activity

Description
PNRI-299 is a selective AP-1 transcription inhibitor with IC50 of 20 uM without affecting NF-kappaB transcription (up to 200 μM) or thioredoxin (up to 200 μM).

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