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Items 201 to 250 of 1758 total

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Catalog No. Product Name Application Product Information Sale Price
A10545

LY2228820 SALE

p38 MAPK inhibitor
LY2228820 is a novel and potent p38MAPK inhibitor with potent antiinflammatory activity.

Special Price Starting at: $90.00

A10978

Voriconazole (Vfend) SALE

CYP17 inhibitor
Voriconazole (Vfend) is a triazole antifungal agent that is available as a lyophilized powder for solution for intravenous infusion.

Special Price Starting at: $40.00

A10077

Andrographolide SALE

Apoptosis Inducer
Andrographolide is an interesting pharmacophore with anticancer and immunomodulatory activities and hence has the potential for being developed as a cancer therapeutic agent.

Special Price Starting at: $40.00

A10882

Synephrine (Oxedrine) SALE

Adrenergic Receptor agonist
Synephrine (Oxedrine) is an amine compound commonly used for weight loss.

Special Price Starting at: $35.00

A10549

LY335979 (Zosuquidar 3HCl) SALE

P-gp modulator
LY335979 (Zosuquidar trihydrochloride) is a potent highly selective P-gp inhibitor.

Special Price Starting at: $50.00

A10844

Silymarin (Silybin B) SALE

-
Silymarin (Silibinin B) inhibits chemically induced urinary bladder tumor growth and progression possibly by inhibiting cell proliferation and enhancing apoptosis.

Special Price Starting at: $60.00

A10119

Bafetinib (INNO-406) SALE

Bcr-Abl inhibitor
Bafetinib ((INNO-406) is a dual Bcr-Abl/Lyn tyrosine kinase inhibitor for the potential treatment of leukemia.

Special Price Starting at: $75.00

A10263

Cyt387 (Momelotinib) SALE

JAK inhibitor
CYT387 is an inhibitor of Janus kinases JAK1 and JAK2, acting as an ATP competitor with IC50 values of 11 and 18 nM, respectively.

Special Price Starting at: $90.00

A10495

Kaempferol SALE

ERRα and ERRγ inverse agonist
Kaempferol is found to inhibit bovine aorta myosin light chain kinase with a Ki of 0.3-0.5 microM and also is found to inhibit VEGF expression and in vitro angiogenesis through a novel ERK-NFκB-cMyc-p21 pathway.

Special Price Starting at: $40.00

A11051

PF299804 (Dacomitinib, PF299) SALE

EGFR inhibitor
PF299804 is a potent, orally available, irreversible inhibitor of tyrosine kinase human epidermal growth factor receptors (HER) 1 (EGFR), HER2, and HER4.

Special Price Starting at: $90.00

A11052

Crenolanib (CP-868596) SALE

PDGFR Inhibitor
Crenolanib (CP-868596) is an orally bioavailable, selective small molecule inhibitor of the PDGFR tyrosine kinase, inhibiting both PDGFRA and PDGFRB at picomolar concentrations.

Special Price Starting at: $90.00

A11053

OSI-906 SALE

IGF-1R inhibitor
OSI-906 is a potential first-in-class selective small molecule, dual kinase inhibitor of both insulin-like growth factor-1 receptor (IGF-1R) and insulin receptor (IR).

Special Price Starting at: $50.00

A10819

Salbutamol sulfate (Albuterol) SALE

Adrenergic Receptor agonist
Salbutamol sulfate (Albuterol) is a short-acting β2-adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma and chronic obstructive pulmonary disease.

Special Price Starting at: $50.00

A10356

LY317615 (Enzastaurin) SALE

PKCβ inhibitor
LY317615 (Enzastaurin) is a potent and selective inhibitor of PKCβ with antiproliferative activity (IC50= ~6 nM).

Special Price Starting at: $40.00

A10982

VX-702 SALE

p38 MAPK inhibitor
VX-702 is an orally bioavailable inhibitor of p38 MAP kinase that inhibits platelet agonist induced p38 activation (IC50= 4 to 20 nM).

Special Price Starting at: $40.00

A10832

Sclareolide (Norambreinolide) SALE

-
Sclareolide (Norambreinolide) is a sesquiterpene lactone natural product .

Special Price Starting at: $40.00

A10994

XAV 939 SALE

PARP inhibitor
XAV 939 is a TNKS inhibitor (IC50 values are 0.011 and 0.004 μM for TNKS1 and TNKS2 respectively).

Special Price Starting at: $55.00

A10154

BMS-794833 SALE

c-Met inhibitor
BMS-794833 is a potent ATP competitive inhibitor to Met and VEGFR-2 with IC50 of 1.7 and 15 nmol.

Special Price Starting at: $100.00

A11055

AMG-458 SALE

c-Met inhibitor
AMG-458 is a potent inhibitor of c-Met with an IC50 value of 60nM and displays selectivity against VEGFR2.

Special Price Starting at: $150.00

A10486

Ispinesib (SB-715992) SALE

KSP Inhibitor
Ispinesib (SB-715992) is a potent inhibitor of kinesin spindle protein, a kinesin motor protein essential for the formation of a bipolar mitotic spindle and cell cycle progression through mitosis.

Special Price Starting at: $90.00

A10492

JNJ-26481585 SALE

HDAC inhibitor
JNJ-26481585 is a pan-HDAC inhibitor with marked potency toward HDAC1 (IC(50), 0.16 nmol/L).

Special Price Starting at: $110.00

A10817

S3I-201 (NSC 74859) SALE

Stat3 Inhibitor
S3I-201 (NSC 74859) is a novel inhibitor of Stat3 that inhibits Stat3, Stat3 complex formation and Stat3-DNA binding activity in vitro (IC50 = 86 ± 33 µM) and Stat3-dependent transcriptional activities.

Special Price Starting at: $40.00

A10983

VX-745 SALE

p38 MAPK inhibitor
VX-745 is a small-molecule inhibitor of MAPK that is reported to be active against several isotypes of p38 MAPK, including p38α, p38βand p38γ .

Special Price Starting at: $60.00

A10175

Candesartan (Atacand) SALE

RAAS antagonist
Candesartan is an angiotensin receptor blocker (also called an angiotensin-II receptor antagonist or an AIIRA).

Special Price Starting at: $40.00

A10025

Linifanib (ABT-869) SALE

VEGFR/PDGFR inhibitor
Linifanib (ABT-869) is a structurally novel, potent inhibitor of RTK, VEGF and PDGF with IC50 of 0.2, 2, 4, and 7 nM for human endothelial cells, PDGFR-β, KDR, and CSF-1R, respectively.

Special Price Starting at: $40.00

A10600

MLN2238 SALE

Proteasome Inhibitor
MLN2238 is a potent reversible and specific β5 site of the 20S proteasome inhibitor with an IC50 value of 3.4 nM.

Special Price Starting at: $90.00

A10058

Aloin (Barbaloin) SALE

Tyrosinase inhibitor
Aloin (Barbaloin) is a yellow crystalline substance obtained from aloe and is reported to be a potent inhibitors of tyrosinase.

Special Price Starting at: $60.00

A10214

Cidofovir (Vistide) SALE

DNA/RNA Synthesis inhibitor
Cidofovir (Vistide) is an antiviral used for the treatment of cytomegalovirus (CMV) infection (ie: retinitis).

Special Price Starting at: $80.00

A10557

Marbofloxacin SALE

Topoisomerase inhibitor
Marbofloxacin is a potent antibiotic of the 3rd generation fluoroquinolone group and acts by inhibiting bacterial DNA replication.

Special Price Starting at: $60.00

A10776

Raltitrexed (Tomudex) SALE

DNA/RNA Synthesis inhibitor
Raltitrexed (Tomudex) is an inhibitor of thymidylate synthase and also is one of the strongest antimetabolites in use.

Special Price Starting at: $40.00

A10939

Topotecan HCl (Hycamtin) SALE

DNA topoisomerase I inhibitor
Topotecan HCl (Hycamtin) is a chemotherapeutic agent that is a topoisomerase inhibitor.

Special Price Starting at: $73.00

A10967

Vatalanib (PTK787) 2HCl SALE

VEGFR inhibitor
Vatalanib (PTK787 or PTK/ZK) is a small molecule protein kinase inhibitor that inhibits angiogenesis that inhibits all known VEGF receptors, as well as platelet-derived growth factor receptor-beta and c-kit, but is most selective for VEGFR-2.

Special Price Starting at: $40.00

A10020

Abiraterone (CB-7598) SALE

CYP17 inhibitor
Abiraterone (CB-7598) inhibits 17 α-hydroxylase/C17,20 lyase (CYP17A1), an enzyme which is expressed in testicular, adrenal, and prostatic tumor tissues.

Special Price Starting at: $40.00

A11058

Abiraterone Acetate (CB7630) SALE

CYP17 inhibitor
Abiraterone acetate (CB7630) is an orally active acetate ester of the steroidal compound Abiraterone with antiandrogen activity. Abiraterone inhibits 17 α-hydroxylase/C17,20 lyase (CYP17A1).

Special Price Starting at: $30.00

A10451

Hexestrol SALE

Estrogen/progestogen Receptor agonist
Hexestrol is a carcinogenic synthetic estrogen that inhibits microtubule polymerization and the formation of ribbon structures. It is an inhibitor of lipid peroxidation.

Special Price Starting at: $40.00

A10326

Docetaxel (Taxotere) SALE

Microtubule Associated inhibitor
Docetaxel (Taxotere) is an antineoplastic agent that acts by disrupting the microtubular network in cells that is essential for mitotic and interphase cellular functions.

Special Price Starting at: $30.00

A10689

Paclitaxel (Taxol) SALE

Microtubule Associated inhibitor
Paclitaxel (Taxol) is a mitotic inhibitor that stabilizes microtubules and as a result, interferes with the normal breakdown of microtubules during cell division.

Special Price Starting at: $30.00

A10973

Vincristine sulfate SALE

Tubulin inhibitor
Vincristine is a mitotic inhibitor, and is used in cancer chemotherapy.

Special Price Starting at: $50.00

A10360

Epothilone B (EPO906) SALE

Microtubule Associated inhibitor
Epothilone B is a macrolide that causes the formation of bundles of intracellular microtubules in non-mitotic cells, induces the formation of hyperstable tubulin polymers, and arrests cell cycling in mitosis.

Special Price Starting at: $40.00

A10290

Dasatinib (BMS-354825) SALE

Abl-Src inhibitor
Dasatinib (BMS-354825) is an oral multi- BCR/ABL and Src family tyrosine kinase inhibitor. The main targets of dasatinib, are BCR/ABL, Src, c-Kit, ephrin receptors, and several other tyrosine kinases, but not erbB kinases such as EGFR or Her2.

Special Price Starting at: $60.00

A11059

BMS-754807 SALE

IGF-1R inhibitor
BMS-754807 is an efficacious, orally active growth factor 1 receptor/insulin receptor family-targeted kinase inhibitor that may act in combination with a wide array of established anticancer agents.

Special Price Starting at: $60.00

A11060

CX-4945 (Silmitasertib) SALE

CK2 inhibitor
CX-4945 is a potent and selective orally bioavailable small molecule inhibitor of CK2 that inhibits human umbilical vein endothelial cell migration, tube formation, and blocks CK2-dependent hypoxia-induced factor 1 alpha (HIF-1α) transcription in cancer cells.

Special Price Starting at: $40.00

A10352

ENMD-2076 SALE

Aurora A / FLT3 Inhibitor
ENMD-2076 has selective activity against Aurora A and Flt3 with IC50 of 14 nM and 1.86 nM, 25-fold selective for Aurora A than over Aurora B and less potent to VEGFR2/KDR and VEGFR3, FGFR1 and FGFR2 and PDGFRα. Phase 2.

Special Price Starting at: $80.00

A10501

Ki16425 SALE

LPA Receptor Antagonist
Ki16425 is a LPA receptor antagonist with selectivity for LPA1 and LPA3 and exhibits Ki values of 0.34, 6.5, and 0.93 ?M for the human LPA1, LPA2, and LPA3 receptors, respectively.

Special Price Starting at: $50.00

A10508

KW-2449 SALE

FLT3/FGFR/Bcr-Abl/Aurora Inhibitor
KW-2449 is a multikinase inhibitor of FLT3, ABL, ABL-T315I, and Aurora kinase.

Special Price Starting at: $50.00

A10247

Curcumol SALE

JAK2 inhibitor
Curcumol induces apoptosis via caspases-independent mitochondrial pathway in human lung adenocarcinoma ASTC-a-1 cells.

Special Price Starting at: $50.00

A10893

Taxifolin SALE

VEGFR-2 Inhibitor
Taxifolin is found to bind at the ATP-binding site on VEGFR-2 kinase with large value of binding energy and act as type I competitive inhibitor.

Special Price Starting at: $50.00

A10442

GSK461364 SALE

PLK Inhibitor
GSK461364 is an ATP-competitive inhibitor of polo-like kinase 1 (Plk1).

Special Price Starting at: $80.00

A10809

Rosiglitazone maleate SALE

PPAR agonist
Rosiglitazone maleate, an antidiabetic drug, works as an insulin sensitizer, by binding to the PPAR receptors in fat cells and making the cells more responsive to insulin.

Special Price Starting at: $40.00

A10076

Andarine (GTX-007) SALE

Androgen Receptor agonist
Andarine (GTX-007) is an investigational selective androgen receptor modulator (SARM).

Special Price Starting at: $90.00

Items 201 to 250 of 1758 total

per page
Page:
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  2. 4
  3. 5
  4. 6
  5. 7

Set Descending Direction