Retinoic Acid Receptors



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Catalog No. Product Name Application Product Information
A16292

AGN 194310

pan-RARs agonist
AGN 194310 is a potent and selective pan-RARs agonist with Kd values of 3/2/5 nM for RARα/β/γ respectively.
A16293

AGN 195183

RARα agonist
AGN 195183 is a potent and selective agonist of RARα (Kd=3 nM) with improved binding selectivity relative to AGN 193836; no activity on RARβ/γ.
A16294

AGN 196996

RARα antagonist
AGN 196996 is a potent and selective RARα antagonist with Ki value of 2 nM; little binding affinity for RARβ(Ki=1087 nM) and RARγ(Ki=8523 nM).
A16295

AGN 205327

RAR agonist
AGN 205327 is a potent synthetic RARs agonist with EC50 of 3766/734/32 nM for RARα/β/γ respectively; no inhibition on RXR.
A16296

AGN 205728

RARγ antagonist
AGN 205728 is a potent and selective RARγ antagonist with Ki/IC95 values of 3 nM/ 0.6 nM; no inhibiton on RARα and RARβ.
A11792 SALE

AM 580

RARα agonist
AM 580 is an analog of retinoic acid that acts as a selective RARα agonist.
A11793

CD 437

RARγ-selective agonist
CD 437 is a synthetic retinoid that is an RARγ-selective agonist.
A12430 SALE

Palovarotene

-
Palovarotene is a novel retinoic acid receptor gamma agonist for the treatment of emphysema
A11589

Tamibarotene

RARα agonist
Tamibarotene is a retinoic acid receptor α (RARα) agonist that induces differentiation (ED50 = 0.79 nM) and apoptosis of HL-60 cells in vitro.
A10944 SALE

Tretinoin

RAR agonist
Tretinoin is an endogenous agonist for retinoic acid receptors with IC50 value of 14 nM for RAR-alpha, RAR-beta and RAR-gamma receptors).
A13007 SALE

TTNPB

RAR agonist
TTNPB enhances reprogramming efficiency in chemically induced pluripotent stem cells (CiPSCs).

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