RIP Kinase



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Catalog No. Product Name Application Product Information
A12615

GSK481

RIP1 inhibitor
GSK481 is a novel benzoxazepinone (BOAz) series of RIP1 inhibitors. Receptor Interacting Protein Kinase 1 (RIP1) has been implicated as a key contributor to inflammation through the regulation of programmed necrosis. Inhibition of this kinase has been shown to hinder cell necrotic death, thereby establishing RIP1 as a viable target for the potential treatment of multiple inflammatory diseases.
A16311

GSK583

RIP2 kinase inhibitor
GSK583 is a highly potent and selective inhibitor of RIP2 Kinase.
A11973

Necrostatin-1

RIPK1 inhibitor
Necrostatin-1 is an ATP-competitive, allosteric inhibitor of receptor-interacting protein kinase 1 (RIPK1) (EC50 = 182 nM).
A16312

RIP2 kinase inhibitor 1

RIP2 kinase inhibitor
RIP2 kinase inhibitor 1 is a receptor interacting protein-2 (RIP2) kinase inhibitor extracted from patent WO/2014043446 A1, compound example 1.
A16313

RIP2 kinase inhibitor 2

RIP2 kinase inhibitor
RIP2 kinase inhibitor 2 is a receptor interacting protein-2 (RIP2) kinase inhibitor extracted from patent WO/2014043437 A1, compound example 9.

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