Ripasudil
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | Ripasudil (K-115) is potent ROCK inhibitor with IC50 of 51 nM and 19 nM for ROCK1 and ROCK2, respectively, used for the treatment of glaucoma and ocular hypertension. | ||
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Catalog Num | A15888 |
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Formula | C15H23ClFN3O4S |
Molecular Weight | 395.88 |
CAS Number | 887375-67-9 |
SMILES | CC1CNCCCN1S(=O)(=O)C2=CC=CC3=CN=CC(=C32)F.O.O.Cl |
Synonyms | K 115, K115, K-115 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | Warmed: 25 mg/mL (63.14 mM) | |
Water | 76 mg/mL (191.97 mM) | ||
Ethanol | Warmed: 5 mg/mL (12.63 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 25.26 mL | 126.3 mL | 252.6 mL |
0.5 mM | 5.05 mL | 25.26 mL | 50.52 mL |
1 mM | 2.53 mL | 12.63 mL | 25.26 mL |
5 mM | 0.51 mL | 2.53 mL | 5.05 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2