SJ 172550

MDMX inhibitor

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Catalog No. A15352

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
SJ 172550 10mg A15352-10

Regular Price: $110.00

Special Price: $93.50

SJ 172550 50mg A15352-50

Regular Price: $450.00

Special Price: $382.50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

SJ 172550 is the first MDMX inhibitor with EC50 of 0.84 uM; binds reversibly to MDMX and effectively kills retinoblastoma cells in which the expression of MDMX is amplified.

SJ 172550

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Chemical Information

Catalog Num A15352
Actions Inhibitor
M. Wt 428.87
Formula C22H21ClN2O5
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 431979-47-4
Synonyms SJ172550, SJ-172550
SMILES code CCOC1=C(C(=CC(=C1)C=C2C(=NN(C2=O)C3=CC=CC=C3)C)Cl)OCC(=O)OC
Chemical Name methyl 2-[2-chloro-6-ethoxy-4-[(3-methyl-5-oxo-1-phenylpyrazol-4-ylidene)methyl]phenoxy]acetate

Biological Activity

Description
SJ 172550 is the first MDMX inhibitor with EC50 of 0.84 uM; binds reversibly to MDMX and effectively kills retinoblastoma cells in which the expression of MDMX is amplified.

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