SPL-B

Catalog No.: A16085
TACC3 inhibitor
SPL-B, Orally active inhibitor of transforming acidic coiled-coil protein (TACC3) that selectively inhibits the nucleation of centrosome microtubules in ovarian cancer cells, without affecting spindle assembly in normal cells.
Grouped product items
Product Name Stock
SPL-B 5mg
SPL-B 10mg
SPL-B 50mg
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Biological Activity
Discription SPL-B, Orally active inhibitor of transforming acidic coiled-coil protein (TACC3) that selectively inhibits the nucleation of centrosome microtubules in ovarian cancer cells, without affecting spindle assembly in normal cells.
Product Information
Catalog Num A16085
Formula C27H22N2O5
Molecular Weight 454.48
CAS Number 1465248-60-5
SMILES CCN(CC1=CC=NC=C1)CC2=C(C=CC3=C2OC(=O)C=C3C4=CC5=CC=CC=C5OC4=O)O
Synonyms Spindlactone B
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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