Stem Cells



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Catalog No. Product Name Application Product Information
A13584

A-3 Hydrochloride

PKA, PKG, Casein Kinase I and II inhibitor
A-3 Hydrochloride is an inhibitor of PKA (cAMP-dependent protein kinase, Ki=4.3μM) and cGMP-dependent protein kinase, Ki=3.8μM, PKC (protein kinase C, Ki=47μM), casein kinase I and II, and MLCK (myosin light chain kinase) ( Ki=7.4μM).
A11060

CX-4945 (Silmitasertib)

CK2 inhibitor
CX-4945 is a potent and selective orally bioavailable small molecule inhibitor of CK2 that inhibits human umbilical vein endothelial cell migration, tube formation, and blocks CK2-dependent hypoxia-induced factor 1 alpha (HIF-1α) transcription in cancer cells.
A16234

CX-4945 sodium salt

CK2 inhibitor
CX-4945 sodium salt is a potent and selective ATP-competitive small molecule protein kinase CK2 inhibitor with a Ki and an IC50 of 0.38 and 1 nM for recombinant human CK2α, respectively.
A13949

D4476

CK1 Inhibitor
D4476 is a cell-permeant inhibitor of casein kinase 1.
A15069

DMAT

CK2 inhibitor
DMAT is a potent and specific CK2 inhibitor with an IC50 of 0.13 uM.
A10344

Ellagic acid

-
Ellagic acid is a natural phenol antioxidant found in numerous fruits and vegetables. The antiproliferative and antioxidant properties of ellagic acid have spurred preliminary research into the potential health benefits of ellagic acid consumption.
A15764

IC 261

CK1 Inhibitor
IC 261 is Casein kinase 1 ?? (CK1??) and CK1 ?? inhibitor.
A12922

ID 8

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ID 8 stimulates proliferation at a steady rate (observed in serum-free media supplemented with 10 μM over a 30 day period).
A12926

Kartogenin

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Kartogenin potently induces differentiation of human mesenchymal stem cells into chondrocytes
A13574

LH 846

CK1 inhibitor
LH 846 is a selective inhibitor of casein kinase (CK) 1δ (IC50 values are 290 nM, 1.3 μM and 2.5 μM for CK1δ, ε and α)
A11781

PF 670462

Casein kinase inhibitor
PF 670462 inhibits PER protein nuclear translocation (EC50 = 290 nM) causing phase shifts in circadian rhythms and attenuates methamphetamine-stimulated locomotion in vivo.
A16235

SR-3029

CK1δ/CK1ε inhibitor
SR-3029 is a potent and highly specific CK1δ/CK1ε inhibitor with the IC50 of 97 nM.
A16236

TA-01

CK inhibitor
TA-01 potently inhibits CK1ε, CK1δ,and p38α (IC50values are 6.4, 6.8, and 6.7 nM respectively).
A15257

TBB

CK2 Inhibitor
TBB is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2)with IC50s of 0.9 and 1.6 uM for rat liver and human recombinant CK2 respectively).
A14101

TTP-22

CK2 inhibitor
TTP 22 is a high affinity, casein kinase 2 (CK2) inhibitor (IC50= 0.1??M, Ki= 40nM). In addition, TTP 22 shows selectivity for CK2 over JNK3, ROCK1, and MET (inhibitory effects displayed at greater than 10 ??M). TTP 22 is highly conserved serine/threonine protein kinase that is also involved in cell proliferation, cell differentiation and apoptosis.

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