All 'γ secretase' Products



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Catalog No. Product Name Application Product Information
A10157

BMS-708163 (Avagacestat)

Gamma-secretase inhibitor
BMS-708163 is an oral gamma secretase inhibitor designed for selective inhibition of amyloid beta synthesis.
A10288 SALE

DAPT (GSI-IX)

Gamma secretase inhibitor
DAPT (GSI-IX) is an inhibitor of γ-secretase that causes a reduction in Aβ40 and Aβ42 levels in human primary neuronal cultures with IC50 values of 115 and 200 nM for total Aβ and Aβ42 respectively.
A15899

L-685458

γ-secretase inhibitor
L-685458 is a specific and potent inhibitor of A beta PP gamma-secretase activity with Ki of 17 nM.
A11176 SALE

LY-411575

Gamma secretase inhibitor

LY-411575 is a selective, cell permeable, small molecule gamma secretase inhibitor.

A13319

PF-03084014

γ-secretase inhibitor
PF-03084014 (PF-3084014) is a selective gamma-secretase inhibitor with IC50 of 6.2 nM in a cell-free assay. Phase 2.
A10802 SALE

RO4929097

Gamma-secretase inhibitor
RO4929097 is an orally bioavailable, small-molecule gamma secretase (GS) inhibitor with an IC50 of 4 nM.
A11174 SALE

YO-01027

γ-secretase inhibitor
YO-01027 is a dipeptidic γ-secretase inhibitor, an antiAlzheimer agent.

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