All 'Aurora C' Products



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Catalog No. Product Name Application Product Information
A10100

Aurora A Inhibitor I

Aurora A Inhibitor

Aurora A Inhibitor I is a potent and selective inhibitor of Aurora A kinase (AurA), with IC50 values to be 3.4 nM (Aurora A) and unusually high selectivity 1000 fold against Aurora B; a useful tool compound for investigating the cellular role of Aurora A kinases.

A15762 SALE

BI-847325

MEK/Aurora Inhibitor
BI-847325 is an orally bioavailable, and selective dual MEK/Aurora kinase inhibitor with IC50 of 3 nM, 25 nM, 15 nM, 25 nM, and 4 nM for Xenopus laevis Aurora B, human Aurora A and Aurora C, as well as human MEK1 and MEK2, respectively. Phase 1.
A10184

CCT129202

Aurora Inhibitor

CCT129202 is a representative of a structurally novel series of imidazopyridine small-molecule inhibitors of Aurora kinase activity. It shows high selectivity for the Aurora kinases over a panel of other kinases tested and inhibits proliferation in multiple cultured human tumor cell lines.

A11081

CCT137690

Aurora Kinase inhibitor
CCT137690 is a potent inhibitor of Aurora kinases that inhibits Aurora A and B kinases with low nanomolar IC50 values in both biochemical and cellular assays.
A13250 SALE

Reversine

Aurora B inhibitor
Reversine, which induces the dedifferentiation and regeneration of human cells, inhibits MPS1 and Aurora B with IC50 of 6 nM and 98.5 nM, respectively.
A10851

SNS-314

Aurora inhibitor
SNS-314, a pan-Aurora kinase inhibitor, shows potent anti-tumor activity and dosing flexibility in vivo.
A10981 SALE

VX-680 (MK-0457, Tozasertib)

Aurora Kinase inhibitor
VX-680 is a potent and selective small-molecule inhibitor of the Aurora kinases.

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