United States
You have no items in your shopping cart.
All 'Bcr-Abl' Products
6 Item(s)
per page
| Catalog No. | Product Name | Application | Product Information |
|---|---|---|---|
A11439 SALE |
GNF 2 |
Bcr-Abl inhibitor |
GNF 2 is a Bcr-abl inhibitor that inhibits proliferation and induces apoptosis in Bcr-abl-expressing cells.
|
A13237 SALE |
GNF-5 |
Bcr-Abl inhibitor |
GNF-5 is a selective allosteric inhibitor of BCR-ABL.
|
A10644 SALE |
Nilotinib (AMN-107) |
Bcr-Abl inhibitor |
Nilotinib is a Bcr-Abl inhibitor with IC50 less than 30 nM.
|
A13120 SALE |
PD173955 |
Bcr-Abl inhibitor |
PD-173955 is a src tyrosine kinase inhibitor. PD173955 inhibited Bcr-Abl-dependent cell growth. PD173955 showed cell cycle arrest in G(1). PD173955 has an IC(50) of 1-2 nM in kinase inhibition assays of Bcr-Abl, and in cellular growth assays it inhibits Bcr-Abl-dependent substrate tyrosine phosphorylation. PD173955 inhibited kit ligand-dependent c-kit autophosphorylation (IC(50) = approximately 25 nM) and kit ligand-dependent proliferation of M07e cells (IC(50) = 40 nM) but had a lesser effect on interleukin 3-dependent (IC(50) = 250 nM) or granulocyte macrophage colony-stimulating factor (IC(50) = 1 microM)-dependent cell growth.
|
A10981 SALE |
VX-680 (MK-0457, Tozasertib) |
Aurora Kinase inhibitor |
VX-680 is a potent and selective small-molecule inhibitor of the Aurora kinases.
|
A10988 |
WP1130 ( Degrasyn ) |
DUB/Bcr/ABL Inhibitor |
WP1130 (Degrasyn) is a novel selective small molecular deubiquitinase inhibitor and a Bcr/Abl destruction pathway activator that specifically and rapidly down-regulates both wild-type and mutant Bcr/Abl protein without affecting bcr/abl gene expression in chronic myelogenous leukemia (CML) cells.
|
6 Item(s)
per page