All 'C-Raf' Products

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Catalog No. Product Name Application Product Information


Raf inhibitor
AZ628 is a RAF inhibitor with IC50 values: ca 30 nM for BRAF V600E and wild-type CRAF and 100 nM for wild-type BRAF.
A11381 SALE

Dabrafenib (GSK2118436A)

Raf inhibitor
Dabrafenib is a potent and selective inhibitor of B-RAF protein kinase carrying V600E mutation, currently in clinical trial.
A11436 SALE

GW 5074

Raf-1 Inhibitor
GW 5074 is a potent, selective and cell-permeable c-Raf1 kinase inhibitor

RO5126766 (CH5126766)

Raf/MEK dual inhibitor
RO5126766, also known as CH5126766, is a protein kinase inhibitor specific for the Raf and MEK mitogen-activated protein kinases (MAPKs) with potential anti-neoplastic activity.
A11077 SALE

ZM 336372

C-Raf inhibitor
ZM 336372 is a potent ATP-competitive inhibitor of Raf-1 in vitro (IC50 = 70 nM) with the paradoxical effect of inducing >100-fold activation of Raf-1 in whole cells.

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