All 'FLT3' Products

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Catalog No. Product Name Application Product Information
A10027 SALE

AC220 (Quizartinib)

FLT3 inhibitor
AC220 (Quizartinib) is a uniquely potent and selective FLT3 inhibitor with IC50 of 0.56 ± 0.3 nM and >10 mM for MC4-11 and A375, respectively.


Dual FLT3/CDK4 inhibitor
AMG-925 is a potent, selective, and bioavailable FLT3/cyclin-dependent kinase 4 (CDK4) dual kinase inhibitor.

AZD 2932

mutil-targeted protein tyrosine kinase inhibitor
AZD2932 is a potent and mutil-targeted protein tyrosine kinase inhibitor with IC50 of 8 nM, 4 nM, 7 nM, and 9 nM for VEGFR-2, PDGFRβ, Flt-3, and c-Kit, respectively.

Go 6976

PKC inhibitor
Go 6976 is a potent protein kinase C (PKC) inhibitor (IC50 = 7.9 nM).

MP470 (MP-470, Amuvatinib)

RTK inhibitor
MP470 is a c-Kit/PDGFR tyrosine kinase inhibitor.
A15520 SALE

Pexidartinib (PLX3397)

CSF1/Kit/FLT3 inhibitor
Pexidartinib is a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential antineoplastic activity.
A10769 SALE

R406 besylate

Syk Inhibitor
R406 is an orally available spleen tyrosine kinase inhibitor with an IC50 of 41 nM.
A10838 SALE

SGI-1776 (free base)

PIM Inhibitor
SGI-1776 is a potent and selective inhibitor of Pim kinases that induces apoptosis in CLL and that the mechanism involves Mcl-1 reduction.

TCS 359

FLT3 inhibitor
TCS 359 is a potent inhibitor of FLT3 receptor tyrosine kinase (IC50 = 42 nM) that displays selectivity over a range of other kinases.
A11082 SALE


JAK inhibitor
TG-101348 is an orally bioavailable, ATP-competitive and selective inhibitor of Janus-associated kinase 2 with potential antineoplastic activity.


JAK2 inhibitor

TG101209, a novel JAK2 inhibitor, has significant in vitro activity in multiple myeloma and displays preferential cytotoxicity for CD45+ myeloma cells.

A10981 SALE

VX-680 (MK-0457, Tozasertib)

Aurora Kinase inhibitor
VX-680 is a potent and selective small-molecule inhibitor of the Aurora kinases.

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