All 'Mdm2' Products



13 Item(s)

per page

Set Descending Direction
Catalog No. Product Name Application Product Information
A14394

AMG232

MDM2 inhibitor
AMG 232 is a highly potent, selective and orally bioavailable piperidinone inhibitor of the MDM2-p53 interaction((SPR KD= 0.045 nM, SJSA-1 EdU IC50=9.1 nM).
A14211

Idasanutlin (RG7388)

MDM2/p53 Inhibitor
Idasanutlin is a potent and selective p53-MDM2 inhibitor.
A13582

MDM2 Inhibitor

MDM2 inhibitor
MDM2 Inhibitor is a cell-permeable boranyl-chalcone exhibiting strong binding to MDM2 and irreversibly disrupts the MDM2/p53 protein complex.
A15440

MI-773

MDM2 inhibitor
MI-773 is an orally available MDM2 antagonist with Ki of 0.88 nM.
A11501 SALE

Nutlin 3a

MDM2 inhibitor
Nutlin 3a is a potent inhibitor of MDM2 (mouse double minute 2) binding to p53 that induces the expression of p53 regulated genes, and shows potent antiproliferative activity in cells expressing functional p53.
A11502

Nutlin 3b

MDM2 inhibitor
Nutlin 3b is a p53/MDM2 antagonist or inhibitor with IC50 value of 13.6 uM, 150-fold less potent (+)-enantiomer of Nutlin-3 as in comparison with opposite (-)-enantiomer Nutlin-3a.
A10657 SALE

Nutlin-3

Mdm2 antagonist
MDM2 antagonist nutlin-3 is a potent inducer of apoptosis.
A15201

p53 and MDM2 proteins-interaction-inhibitor chiral

p53-MDM2 interaction inhibitor
p53 and MDM2 proteins-interaction-inhibitor chiral is an inhibitor of the interaction between p53 and MDM2 proteins.
A15202

p53 and MDM2 proteins-interaction-inhibitor racemic

p53-MDM2 interaction inhibitor
p53 and MDM2 proteins-interaction-inhibitor racemic is an inhibitor of the interaction between p53 and MDM2 proteins.
A11931 SALE

RITA (NSC 652287)

p53 activator
RITA, also referred to as NSC 652287, is a trycyclic thiophene derivative that binds to MDM2, disrupting the MDM2-p53 complex and subsequently activating p53 and inducing apoptosis.
A11943

Tenovin-1

p53 activator
Tenovin-1 is a small molecule activator of p53 transcriptional activity that protects against MDM2-mediated p53 degradation.
A15353

WR 1065

P53/p21waf-1/MDM2 activator
WR 1065, a dephosphorylated metabolite of amifostine (Ethyol), can protect against the immediate and delayed effects of radiation exposure.
A14118

YH239-EE

Mdm2 inhibitor
YH239-EE is a potent p53-MDM2 antagonist and an apoptosis inducer.

13 Item(s)

per page

Set Descending Direction