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All 'PI3Kβ' Products



17 Item(s)

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Catalog No. Product Name Application Product Information
A15901

AMG319

PI3Kδ inhibitor
AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, >47-fold selectivity over other PI3Ks. Phase 2.
A10088

AS-605240

PI3K Inhibitor
AS-605240 is an orally active inhibitor of PI3-kinase γ that inhibits human recombinant PI3Kγ, α, β, and δ in an ATP-competitive manner with IC50 values of 8, 60, 270, and 300 nM, respectively.
A10112 SALE

AZD6482

PI3K inhibitor
AZD6482 is a PI3Kbeta inhibitor (IC50=0.021M) used in antithrombotic therapy.
A11766 SALE

BAY 80-6946 (Copanlisib)

PI3K inhibitor
BAY 80-6946 is a phosphoinositide 3-kinase (PI3K) inhibitor with potential antineoplastic activity.
A11363 SALE

CZC24832

PI3K inhibitor
CZC24832 is a selective inhibitor of PI 3-Kinase γ (IC50 = 1.0 μM in a PI 3-Kγ-dependent fMLP-induced neutrophil migration assay).
A10438 SALE

GSK1059615

mTOR/PI3K Inhibitor
GSK1059615 is a potent, reversible, ATP-competitive, thiazolidinedione inhibitor of PI3Kα (IC50 = 2 nM).
A11784 SALE

GSK2636771

PI3K Inhibitor
GSK2636771 is a potent, orally bioavailable, PI3K beta-selective inhibitor.
A10463 SALE

IC-87114

PI3K Inhibitor
IC-87114 was the first isoform-selective PI3K inhibitor :p110M-NM-4(IC50 = 0.13 M-BM-5M) vs. p110M-NM-1(IC50 = 200 M-BM-5M), p110M-NM-2(IC50 = 16 M-BM-5M) and p110M-NM-3(IC50 = 61 M-BM-5M).
A13224 SALE

KU 0060648

DNA-PK inhibitor
KU0060648 is a potent and selective inhibitor of DNA-dependent protein kinase (DNA-PK), (IC50 = 8.6 nM); with 20-1000 fold selectivity for DNA-PK over other PIKKs and a panel of 60 kinases. KU-0060648 enhances HDR efficiency and attenuates NHEJ frequency.
A11162 SALE

NVP-BGT226

PI3K inhibitor

NVP-BGT226, novel phosphoinositide 3-kinase/mTOR dual inhibitor, displays potent growth-inhibitory activity against human head and neck cancer cells in vitro and in vivo.

A10730 SALE

PIK-90

PI3K Inhibitor
PIK-90 is a synthetic phosphoinositide 3-kinase (PI3K) inhibitor with IC50 values (nM) of 11, 350, 18, and 58 for p110 α, β, γ and δ isoforms, low mTOR activity.
A11089

PKI-402

PI3K inhibitor
PKI-402 is a dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor.
A11956

TG 100713

PI3K inhibitor
TG 100713 is an inhibitor of PI3-kinase that inhibits endothelial cell proliferation.
A10922 SALE

TG100-115

PI3K Inhibitor
TG100-115 inhibits PI3K γ and -δ(IC50 values of 83 and 235 nM, respectively).
A12480 SALE

VS-5584

PI3K/mTOR inhibitor
VS-5584 is a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer.
A15283

XL-147 (Pilaralisib)

PI3K Inhibitor
XL147 is a potent, orally bioavailable inhibitor of the class I PI3K family of lipid kinases.
A11014 SALE

ZSTK474

PI3K inhibitor
ZSTK474 is an ATP-competitive inhibitor of class I phosphatidylinositol 3 kinase isoforms.

17 Item(s)

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