All 'Src' Products



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Catalog No. Product Name Application Product Information
A10161 SALE

Bosutinib (SKI-606)

Src inhibitor
Bosutinib (SKI-606) is a tyrosine kinase inhibitor undergoing research for use in the treatment of cancer.
A10290 SALE

Dasatinib (BMS-354825)

Abl-Src inhibitor
Dasatinib (BMS-354825) is an oral multi- BCR/ABL and Src family tyrosine kinase inhibitor. The main targets of dasatinib, are BCR/ABL, Src, c-Kit, ephrin receptors, and several other tyrosine kinases, but not erbB kinases such as EGFR or Her2.
A11177 SALE

KX2-391

Src inhibitor

KX2-391 is a novel non-ATP competitive substrate-pocket directed SRC inhibitor.

A13415

MCB-613

SRC stimulator
MCB-613 is a potent, pan steroid receptor coactivator (SRC) stimulator.
A16240

MNS

Src/Syk inhibitor
MNS is a potent and selective inhibitor of Src and Syk tyrosine kinases.
A13120 SALE

PD173955

Bcr-Abl inhibitor
PD-173955 is a src tyrosine kinase inhibitor. PD173955 inhibited Bcr-Abl-dependent cell growth. PD173955 showed cell cycle arrest in G(1). PD173955 has an IC(50) of 1-2 nM in kinase inhibition assays of Bcr-Abl, and in cellular growth assays it inhibits Bcr-Abl-dependent substrate tyrosine phosphorylation. PD173955 inhibited kit ligand-dependent c-kit autophosphorylation (IC(50) = approximately 25 nM) and kit ligand-dependent proliferation of M07e cells (IC(50) = 40 nM) but had a lesser effect on interleukin 3-dependent (IC(50) = 250 nM) or granulocyte macrophage colony-stimulating factor (IC(50) = 1 microM)-dependent cell growth.
A15518 SALE

SU6656

SRC inhibitor
SU6656 is a selective inhibitor of Src kinases, Including Src, Yes, Lyn, and Fyn (IC50 = 280, 20, 130, 170 nM, respectively).
A14117 SALE

WH 4-023

dual Lck/Src inhibitor
WH-4-023 is a potent and selective dual Lck/Src inhibitor with IC50 of 2 nM/6 nM for Lck and Src kinase respectively.
A14049

WHI-P 154

JAK3 inhibitor
WHI-P 154 is a JAK3 inhibitor with IC50 = 1.8uM. WHI-P 154 also Inhibits STAT1 activation, iNOS expression and NO production in macrophages in vitro.
A11955

ZM 306416 hydrochloride

VEGFR Inhibitor
ZM 306416 is a VEGF receptor tyrosine kinase inhibitor that inhibits KDR (IC50 = 100 nM) and Flt (IC50 = 2 uM) tyrosine kinases.

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