All 'Topoisomerase II' Products



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Catalog No. Product Name Application Product Information
A10041 SALE

Adriamycin

topoisomerase II inhibitor

Adriamycin is an anthracycline antibiotic, it works by intercalating DNA, while most serious adverse effect being life-threatening heart damage. It is commonly used in the treatment of a wide range of cancers, including hematological malignancies, many types of carcinoma, and soft tissue sarcomas.

A10071 SALE

Amonafide (AS1413)

Topoisomerase inhibitor

Amonafide is a DNA intercalator and topoisomerase II inhibitor for the treatment of neoplastic diseases, one of Antitumor agent.

A10344 SALE

Ellagic acid

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Ellagic acid is a natural phenol antioxidant found in numerous fruits and vegetables. The antiproliferative and antioxidant properties of ellagic acid have spurred preliminary research into the potential health benefits of ellagic acid consumption.
A10373 SALE

Etoposide (VP-16)

Topoisomerase II inhibitor
Etoposide forms a ternary complex with DNA and the topoisomerase II enzyme (which aids in DNA unwinding), prevents re-ligation of the DNA strands, and by doing so causes DNA strands to break. Therefore, this causes errors in DNA synthesis and promotes apoptosis of the cancer cell.
A11861

Flumequine

Topoisomerase II inhibitor
Flumequine is a synthetic chemotherapeutic antibiotic which affecting mammalian chromosome and DNA unwinding at the level of gyrase/topoisomerases.
A10465

Idarubicin HCl

Topoisomerase inhibitor
Idarubicin is an anthracycline antibiotic that is an anti-leukemia agent with higher DNA binding capacity and greater cytotoxicity than daunorubicin.
A10557 SALE

Marbofloxacin

Topoisomerase inhibitor
Marbofloxacin is a potent antibiotic of the 3rd generation fluoroquinolone group and acts by inhibiting bacterial DNA replication.
A10595 SALE

Mitoxantrone

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Mitoxantrone is a synthetic antineoplastic anthracenedione (IC50 = 0.42 mM).
A10596

Mitoxantrone Hydrochloride

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Mitoxantrone Dihydrochloride is an antiviral, antibacterial, antiprotozoal, immunomodulating, and antineoplastic cytostatic anthraquinone derivative.
A10609 SALE

Moxifloxacin HCl

Topoisomerase inhibitor
Moxifloxacin is a quinolone/fluoroquinolone antibiotic.
A10666 SALE

Ofloxacin (DL8280)

Topoisomerase inhibitor
Ofloxacin is a synthetic broad-spectrum antimicrobial agent.
A10735 SALE

Pirarubicin

Topoisomerase II inhibitor
Pirarubicin is an analogue of the anthracycline anti-neoplastic doxorubicin. Intercalates into DNA and interacts with Topo II (topoisomerase II) and supressing DNA replication
A10907

Teniposide

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Teniposide is a semisynthetic derivative of podophyllotoxin with antineoplastic activity.
A15280

Voreloxin Hydrochloride

Topoisomerase inhibitor
Voreloxin Hcl is a small molecule and a naphthyridine analogue with antineoplastic activity; inhibitor of Topo II.

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