All 'p110α' Products



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Catalog No. Product Name Application Product Information
A11023 SALE

GDC-0980 (Apitolisib, RG7422)

mTOR/PI3K Inhibitor
GDC-0980 (RG7422) is a selective, potent, orally bioavailable inhibitor of Class I PI3 kinase and mTOR kinase (TORC1/2) with in vitro IC50 of 5, 27, 7 and 14 nM for p110 α, β, δ and γ isoforms, respectively.
A10547 SALE

LY294002

PI3K Inhibitor
LY294002 is a PI3k inhibitor (cell IC50 about 10 μM) and a casein kinase II inhibitor.
A12889

PF-4989216

PI3K inhibitor
PF-4989216 is a potent and selective PI3K inhibitor with IC50 of 2 nM, 142 nM, 65 nM, 1 nM, and 110 nM for p110??, p110??, p110??, p110??, and VPS34, respectively.
A10727 SALE

PIK-293

PI3K inhibitor
PIK-293 is a PI3-K inhibitor. PIK-293 inhibits the p110α, p110β, p110δ. PIK-293 is the parent compound of PIK-294.
A10729

PIK-75

PI3K Inhibitor
PIK-75 is an imidazopyridine that selectively inhibits p110α with an IC50 value of 5.8 nM.2 It inhibits p110γ and p110β considerably less effectively with IC50 values of 0.076 µM and 1.3 µM, respectively.
A11064 SALE

YM201636

PI3K Inhibitor
YM201636 is a cell-permeable and selective inhibitor of PIKfyve (IC50 = 33 nM).

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