Telotristat Etiprate

TPH inhibitor

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Catalog No. A14299

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Telotristat Etiprate 5mg A14299-5
$150.00
Telotristat Etiprate 10mg A14299-10
$250.00
Telotristat Etiprate 25mg A14299-25
$500.00
Telotristat Etiprate 10mM * 1mL in DMSO A14299-10mM-D
$285.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity.

Telotristat Etiprate

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Chemical Information

Catalog Num A14299
Actions Inhibitor
M. Wt 754.15
Formula C27H26ClF3N6O3.C9H9NO3
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 11137608-69-5
Synonyms LX 1606 Hippurate
SMILES code CCOC(=O)[[email protected]](CC1=CC=C(C=C1)C2=CC(=NC(=N2)N)O[[email protected]](C3=C(C=C(C=C3)Cl)N4C=CC(=N4)C)C(F)(F)F)N.C1=CC=C(C=C1)C(=O)NCC(=O)O
Chemical Name L-Phenylalanine, 4-[2-amino-6-[(1R)-1-[4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]-4-pyrimidinyl]-, ethyl ester, compd. with N-benzoylglycine (1:1)

Biological Activity

Description
Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity.
Targets
Tryptophan hydroxylase

Solubility

Solubility (25°C)* In vitro DMSO 100 mg/mL (132.59 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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