Toll-like Receptors

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Catalog No. Product Name Application Product Information
A13251 SALE


TLR7 agonist
GS-9620 is a potent and selective orally active small molecule agonist of Toll-like receptor 7.
A10469 SALE

Imiquimod (Aldara)

TLR7 agonist
Imiquimod (Aldara) is a a heterocyclic imidazoquinoline amide that acts as an immune response modifier.


TLR7 agonist
Isatoribine is a novel guanosine analogue showing immunostimulatory activity both in vivo and in vitro.


TLR7/8 Agonist
Resiquimod is an immune response modifier that acts as a potent TLR 7/8 agonist. Phase 2.

TAK-242 S enantiomer

TLR4 Inhibitor
S enantiomer of TAK-242. TAK-242 (Resatorvid), a small-molecule inhibitor of Toll-like receptor (TLR) 4 signaling. TAK-242 is in treatment of sepsis and septic shock.

Toll-Like Receptor 7 Ligand II

TLR7 Ligand
Toll-Like Receptor 7 Ligand II is a cell-permeable hydroxyadenine compound which acts as a potent and highly specific TLR7 (toll-like receptor 7) agonist without any detectable activity towards TLR2/3/5/8/9. It is shown to be 10-times more potent than R848 in stimulating the production of TLR7-dependent cytokines in cultures in vitro .

Toll-like receptor modulator

Toll-like receptors (TLRs) are a class of proteins that play a key role in the innate immune system.
A12548 SALE


TLR4 Inhibitor
VGX-1027 displays immunomodulatory and anti-inflammatory activities by inhibiting toll-like receptor 4 (TLR4) signaling.


TLR8 agonist
VTX-2337 is a small-molecule Toll-like receptor 8 (TLR8) agonist with potential immunostimulating and antineoplastic activities.

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