Topotecan HCl (Hycamtin)

Catalog No.: A10939
DNA topoisomerase I inhibitor
Topotecan HCl (Hycamtin) is a chemotherapeutic agent that is a topoisomerase inhibitor.
Grouped product items
Product Name Price Stock Qty
Topotecan HCl 50mg
$125.00
In stock
Topotecan HCl 100mg
$165.00
In stock
Topotecan HCl 200mg
$250.00
In stock
Topotecan HCl (Hycamtin) 10mM * 1mL in DMSO
$55.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription Topotecan HCl (Hycamtin) is a chemotherapeutic agent that is a topoisomerase inhibitor.
Targets
Target Value
Product Information
Catalog Num A10939
Formula C23H23N3O5 .HCl
Molecular Weight 457.9
CAS Number 119413-54-6
SMILES CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=C(C5=C4)CN(C)C)O)O.Cl
Synonyms Hycamtin
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 87 mg/mL (189.99 mM)
Water 87 mg/mL (189.99 mM)
Ethanol Insoluble
In vivo Saline 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.84 mL 109.19 mL 218.39 mL
0.5 mM 4.37 mL 21.84 mL 43.68 mL
1 mM 2.18 mL 10.92 mL 21.84 mL
5 mM 0.44 mL 2.18 mL 4.37 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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