Verteporfin

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YAP inhibitor

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Catalog No. A12658

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Verteporfin 5mg A12658-5

Regular Price: $80.00

Special Price: $68.00

Verteporfin 10mg A12658-10

Regular Price: $120.00

Special Price: $102.00

Verteporfin 25mg A12658-25

Regular Price: $240.00

Special Price: $204.00

Verteporfin 50mg A12658-50

Regular Price: $400.00

Special Price: $340.00

Verteporfin 10mM * 1mL in DMSO A12658-10mM-D

Regular Price: $120.00

Special Price: $102.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Verteporfin is a small molecule that inhibits TEAD–YAP association and YAP-induced liver overgrowth. It is also a potent second-generation photosensitizing agent derived from porphyrin.

Verteporfin

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Chemical Information

Catalog Num A12658
Actions Inhibitor
M. Wt 718.79
Formula C41H42N4O8
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 129497-78-5
Synonyms Visudyne, DB00460??CL 318,952??Benzoporphyrin D??Bpd-MA??AIDS350621??AIDS-350621??Benzoporphyrin derivative monoacid ring A.
SMILES code CC1=C(C2=CC3=NC(=CC4=C(C(=C(N4)C=C5C6(C(C(=CC=C6C(=N5)C=C1N2)C(=O)OC)C(=O)OC)C)C)CCC(=O)OC)C(=C3C)CCC(=O)O)C=C.CC1=C(C2=CC3=NC(=CC4=C(C(=C(N4)C=C5C6(C(C(=CC=C6C(=N5)C=C1N2)C(=O)OC)C(=O)OC)C)C)CCC(=O)O)C(=C3C)CCC(=O)OC)C=C
Chemical Name trans-3,4-Dicarboxy-4,4a-dihydro-4a,8,14,19-tetramethyl-18-vinyl-23H,25H-benzo(b)porphine-9,13-dipropionic acid 3,4,9-trimethyl ester

Biological Activity

Description
Verteporfin is a small molecule that inhibits TEAD–YAP association and YAP-induced liver overgrowth. It is also a potent second-generation photosensitizing agent derived from porphyrin.
Targets
VDA (Endothelial cells)

Solubility

Solubility (25°C)* In vitro DMSO 100 mg/mL (139.12 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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