A66

Catalog No.: A11202

PI3K inhibitor

A66

A66 Chemical Structure

CAS NO. 1166227-08-2

The S-enantiomer of A66 is a potent inhibitor of the p110alpha isoform of PI 3-kinase (PIK3CA).

Availability: In stock

Package Price Qty
5 mg
$120.00
10 mg
$220.00
50 mg
$650.00
100 mg
$1,050.00
10mM * 1mL in DMSO
$140.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

The S-enantiomer of A66 is a potent inhibitor of the p110alpha isoform of PI 3-kinase (PIK3CA).
In vitro (25°C) DMSO 79 mg/mL (200.74 mM)
Water <1 mg/mL (<1 mM)
Ethanol 1 mg/mL (2.54 mM)
In vivo 15% Captisol 8 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.41 mL 127.06 mL 254.11 mL
0.5 mM 5.08 mL 25.41 mL 50.82 mL
1 mM 2.54 mL 12.71 mL 25.41 mL
5 mM 0.51 mL 2.54 mL 5.08 mL

*The above data is based on the productmolecular weight 393.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11202
Actions Inhibitor
M. Wt 393.53
Formula C17H23N5O2S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1166227-08-2
Synonyms A-66
SMILES CC1=C(SC(=N1)NC(=O)N2CCC[[email protected]]2C(=O)N)C3=CSC(=N3)C(C)(C)C

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