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- Subhajit Chatterjee, .et al. PARP inhibitor Veliparib (ABT-888) enhances the anti-angiogenic potentiality of Curcumin through deregulation of NECTIN-4 in oral cancer: Role of nitric oxide (NO), Cell Signal, 2021, Apr;80:109902 PMID: 33373686
Biological Activity
ABT-888(Veliparib) is a potential anti-cancer drug acting as a PARP inhibitor.
| In vitro (25°C) | DMSO | 17 mg/mL (69.58 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 0.5% methylcellulose+0.2% Tween 80 | 4 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 40.93 mL | 204.67 mL | 409.33 mL |
| 0.5 mM | 8.19 mL | 40.93 mL | 81.87 mL |
| 1 mM | 4.09 mL | 20.47 mL | 40.93 mL |
| 5 mM | 0.82 mL | 4.09 mL | 8.19 mL |
*The above data is based on the productmolecular weight 244.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10026 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 912444-00-9 |
| Formula | C13H16N4O |
| M. Wt | 244.3 |
| Purity | >98% |
| Synonyms | ABT888 |
| SMILES | O=C(C1=C2NC([[email protected]@]3(NCCC3)C)=NC2=CC=C1)N |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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