AEE788

Catalog No.: A10043
EGFR inhibitor
AEE788 is an orally bioavailable multiple-receptor tyrosine kinase inhibitor that inhibits phosphorylation of the tyrosine kinases of EGFR, HER2 and VEGF2.
Grouped product items
Product Name Price Stock Qty
AEE788 5mg
$70.00
In stock
AEE788 10mg
$120.00
In stock
AEE788 25mg
$220.00
In stock
AEE788 50mg
$400.00
In stock
AEE788 10mM * 1mL in DMSO
$165.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's AEE788 has been cited by 1 publications
  • Bopei Cui, .et al. , Signal Transduct Target Ther, 2023, Sep 25;8(1):366 PMID: 37743418
  • Biological Activity
    Discription AEE788 is an orally bioavailable multiple-receptor tyrosine kinase inhibitor that inhibits phosphorylation of the tyrosine kinases of EGFR, HER2 and VEGF2.
    Targets
    Target Value
    Product Information
    Catalog Num A10043
    Formula C27H32N6
    Molecular Weight 440.6
    CAS Number 497839-62-0
    SMILES CCN1CCN(CC1)CC2=CC=C(C=C2)C3=CC4=C(N3)N=CN=C4N[C@H](C)C5=CC=CC=C5
    Synonyms NVP-AEE788
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 81 mg/mL (183.84 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 22.7 mL 113.48 mL 226.96 mL
    0.5 mM 4.54 mL 22.7 mL 45.39 mL
    1 mM 2.27 mL 11.35 mL 22.7 mL
    5 mM 0.45 mL 2.27 mL 4.54 mL
    Useful Calculator

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    This equation is commonly abbreviated as: C1V1 = C2V2

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