AG-120 (Ivosidenib)

Catalog No.: A14386

IDH1 inhibitor

AG-120 (Ivosidenib)

AG-120 (Ivosidenib) Chemical Structure

CAS NO. 1448346-63-1

AG-120 is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity.

Availability: In stock

Package Price Qty
5 mg
$120.00
10 mg
$220.00
25 mg
$450.00
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Biological Activity

AG-120 is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity.
In vitro DMSO 95 mg/mL (162.95 mM)
Water Insoluble
Ethanol 95 mg/mL (162.95 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.15 mL 85.77 mL 171.54 mL
0.5 mM 3.43 mL 17.15 mL 34.31 mL
1 mM 1.72 mL 8.58 mL 17.15 mL
5 mM 0.34 mL 1.72 mL 3.43 mL

*The above data is based on the productmolecular weight 582.97. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14386
Actions Inhibitor
CAS No. 1448346-63-1
Formula C28H22ClF3N6O3
M. Wt 582.97
Purity >98%
Synonyms AG120, AG 120, Ivosidenib
SMILES C1CC(=O)N(C1C(=O)N(C2=CC(=CN=C2)F)C(C3=CC=CC=C3Cl)C(=O)NC4CC(C4)(F)F)C5=NC=CC(=C5)C#N
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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