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AG-120 (Ivosidenib)

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IDH1 inhibitor

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Catalog No. A14386

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
AG-120 5mg A14386-5

Regular Price: $120.00

Special Price: $108.00

AG-120 10mg A14386-10

Regular Price: $220.00

Special Price: $198.00

AG-120 25mg A14386-25

Regular Price: $450.00

Special Price: $405.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

AG-120 is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity.

AG-120 (Ivosidenib)

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Chemical Information

Catalog Num A14386
Actions Inhibitor
M. Wt 582.97
Formula C28H22ClF3N6O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1448346-63-1
Synonyms AG120, AG 120, Ivosidenib
SMILES C1CC(=O)N(C1C(=O)N(C2=CC(=CN=C2)F)C(C3=CC=CC=C3Cl)C(=O)NC4CC(C4)(F)F)C5=NC=CC(=C5)C#N

Biological Activity

Description
AG-120 is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.15 mL 85.77 mL 171.54mL
0.5 mM 3.43 mL 17.15 mL 34.31 mL
1 mM 1.72 mL 8.58 mL 17.15 mL
5 mM 0.34 mL 1.72 mL 3.43 mL

*The above data is based on the productmolecular weight 582.97. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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