Signaling Pathway
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| Discription | AG-120 is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity. | ||
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| Targets |
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| Catalog Num | A15869 |
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| Formula | C28H22ClF3N6O3 |
| Molecular Weight | 582.96 |
| CAS Number | 1448347-49-6 |
| SMILES | O=C([C@H](CC1)N(C2=NC=CC(C#N)=C2)C1=O)N([C@@H](C3=CC=CC=C3Cl)C(NC4CC(F)(F)C4)=O)C5=CC(F)=CN=C5 |
| Synonyms | Ivosidenib |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 92 mg/mL (157.81 mM) | |
| Water | Insoluble | ||
| Ethanol | 92 mg/mL (157.81 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.15 mL | 85.77 mL | 171.54 mL |
| 0.5 mM | 3.43 mL | 17.15 mL | 34.31 mL |
| 1 mM | 1.72 mL | 8.58 mL | 17.15 mL |
| 5 mM | 0.34 mL | 1.72 mL | 3.43 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
