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AGI-5198 (IDH-C35)


IDH1 inhibitor

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Catalog No. A12902

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
AGI-5198 (IDH-C35) 5mg A12902-5

Regular Price: $70.00

Special Price: $63.00

AGI-5198 (IDH-C35) 10mg A12902-10

Regular Price: $110.00

Special Price: $99.00

AGI-5198 (IDH-C35) 25mg A12902-25

Regular Price: $180.00

Special Price: $162.00

AGI-5198 (IDH-C35) 50mg A12902-50

Regular Price: $210.00

Special Price: $189.00

AGI-5198 (IDH-C35) 10mM * 1mL in DMSO A12902-10mM-D

Regular Price: $170.00

Special Price: $153.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

AGI-5198, also know as IDH-C35, is the a very potent and selective mutant IDH1 inhibitor that was shown to potential anticancer activity.

AGI-5198 (IDH-C35)

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Chemical Information

Catalog Num A12902
Actions Inhibitor
M. Wt 462.56
Formula C27H31FN4O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1355326-35-0
Synonyms AGI5198,AGI 5198, IDHC35

Biological Activity

AGI-5198, also know as IDH-C35, is the a very potent and selective mutant IDH1 inhibitor that was shown to potential anticancer activity.
R132H-IDH1 R132C-IDH1
70 nM0.16 μM


Solubility (25°C) * In vitro DMSO 24 mg/mL (51.88 mM)
Water <1 mg/mL (<1 mM)
Ethanol 14 mg/mL (30.26 mM)
In vivo 0.5% methylcellulose/0.2% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.62 mL 108.09 mL 216.19mL
0.5 mM 4.32 mL 21.62 mL 43.24 mL
1 mM 2.16 mL 10.81 mL 21.62 mL
5 mM 0.43 mL 2.16 mL 4.32 mL

*The above data is based on the productmolecular weight 462.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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