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Aliskiren (CGP 60536)

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Renin inhibitor

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Catalog No. A11616

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Aliskiren 5mg A11616-5

Regular Price: $40.00

Special Price: $36.00

Aliskiren 10mg A11616-10

Regular Price: $60.00

Special Price: $54.00

Aliskiren 50mg A11616-50

Regular Price: $128.00

Special Price: $115.20

Aliskiren 100mg A11616-100

Regular Price: $200.00

Special Price: $180.00

Aliskiren (CGP 60536) 10mM * 1mL in DMSO A11616-10mM-D

Regular Price: $103.00

Special Price: $92.70

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Aliskiren is an orally active, synthetic nonpeptide renin inhibitor.

Aliskiren (CGP 60536)

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Publications citing Adooq Products
Aliskiren (CGP 60536) Citations (1)
  • Karibe T,et al. Curcumin as an In Vivo Selective Intestinal Breast Cancer Resistance Protein Inhibitor in Cynomolgus Monkeys, Drug Metab Dispos, 2018, May;46(5):667-679 29358184

Chemical Information

Catalog Num A11616
Actions Inhibitor
M. Wt 551.8
Formula C30H53N3O6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 173334-57-1
Synonyms CGP-60536, CGP60536, Tekturna
SMILES code CC(C)[[email protected]@H](CC1=CC(=C(C=C1)OC)OCCCOC)C[[email protected]@H]([[email protected]](C[[email protected]@H](C(C)C)C(=O)NCC(C)(C)C(=O)N)O)N
Chemical Name (2S,4S,5S,7S)-5-amino-N-(2-carbamoyl-2,2-dimethylethyl)-4-hydroxy-7-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-8-methyl-2-(propan-2-yl)nonanamide

Biological Activity

Description
Aliskiren is an orally active, synthetic nonpeptide renin inhibitor.

Solubility

Solubility (25°C)* In vitro DMSO 100 mg/mL (163.98 mM)
Water 100 mg/mL (163.98 mM)
Ethanol 100 mg/mL (163.98 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.12 mL 90.61 mL 181.23mL
0.5 mM 3.62 mL 18.12 mL 36.25 mL
1 mM 1.81 mL 9.06 mL 18.12 mL
5 mM 0.36 mL 1.81 mL 3.62 mL

*The above data is based on the productmolecular weight 551.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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