Aliskiren (CGP 60536)

Catalog No.: A11616

Renin inhibitor

Aliskiren (CGP 60536)

Aliskiren (CGP 60536) Chemical Structure

CAS NO. 173334-57-1

Aliskiren is an orally active, synthetic nonpeptide renin inhibitor.

Availability: In stock

Package Price Qty
5 mg
$40.00
10 mg
$60.00
50 mg
$128.00
100 mg
$200.00
10mM * 1mL in DMSO
$103.00
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  • Karibe T, .et al. Curcumin as an In Vivo Selective Intestinal Breast Cancer Resistance Protein Inhibitor in Cynomolgus Monkeys, Drug Metab Dispos, 2018, May;46(5):667-679 PMID: 29358184

Biological Activity

Aliskiren is an orally active, synthetic nonpeptide renin inhibitor.
In vitro DMSO 85 mg/mL (154.05 mM)
Water 5 mg/mL (9.06 mM)
Ethanol 85 mg/mL (154.05 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.12 mL 90.61 mL 181.23 mL
0.5 mM 3.62 mL 18.12 mL 36.25 mL
1 mM 1.81 mL 9.06 mL 18.12 mL
5 mM 0.36 mL 1.81 mL 3.62 mL

*The above data is based on the productmolecular weight 551.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11616
Actions Inhibitor
CAS No. 173334-57-1
Formula C30H53N3O6
M. Wt 551.8
Purity >98%
Synonyms CGP-60536, CGP60536, Tekturna
SMILES CC(C)[[email protected]@H](CC1=CC(=C(C=C1)OC)OCCCOC)C[[email protected]@H]([[email protected]](C[[email protected]@H](C(C)C)C(=O)NCC(C)(C)C(=O)N)O)N
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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