Alogliptin

Catalog No.: A13571

DPP-4 inhibitor

Alogliptin

Alogliptin Chemical Structure

CAS NO. 850649-61-5

Alogliptin is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9.

Availability: In stock

Package Price Qty
5 mg
$54.00
10 mg
$92.00
25 mg
$162.00
10mM * 1mL in DMSO
$120.00
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Biological Activity

Alogliptin is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9.
Targets
DPP-4
<10 nM
In vitro DMSO 59 mg/mL (173.84 mM)
Water 16 mg/mL (47.14 mM)
Ethanol 59 mg/mL (173.84 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.46 mL 147.32 mL 294.64 mL
0.5 mM 5.89 mL 29.46 mL 58.93 mL
1 mM 2.95 mL 14.73 mL 29.46 mL
5 mM 0.59 mL 2.95 mL 5.89 mL

*The above data is based on the productmolecular weight 339.397. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13571
Actions Inhibitor
CAS No. 850649-61-5
Formula C18H21N5O2
M. Wt 339.397
Purity >98%
Synonyms SYR-322, Axagliptin hydrate
SMILES CN1C(=O)C=C(N(C1=O)CC2=CC=CC=C2C#N)N3CCC[[email protected]](C3)N
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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