Alogliptin

Catalog No.: A13571

DPP-4 inhibitor

Alogliptin Chemical Structure

CAS NO. 850649-61-5

Alogliptin is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9.

Availability: In stock

Package Price Qty
5 mg
$90.00
10 mg
$150.00
25 mg
$300.00
10mM * 1mL in DMSO
$120.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Alogliptin is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9.
Targets
DPP-4
<10 nM
In vitro (25°C) DMSO 68 mg/mL (200.35 mM)
Water 2 mg/mL (5.89 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% methylcellulose 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.46 mL 147.32 mL 294.64 mL
0.5 mM 5.89 mL 29.46 mL 58.93 mL
1 mM 2.95 mL 14.73 mL 29.46 mL
5 mM 0.59 mL 2.95 mL 5.89 mL

*The above data is based on the productmolecular weight 339.397. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13571
Actions Inhibitor
M. Wt 339.397
Formula C18H21N5O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 850649-61-5
Synonyms SYR-322, Axagliptin hydrate
SMILES CN1C(=O)C=C(N(C1=O)CC2=CC=CC=C2C#N)N3CCC[[email protected]](C3)N

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