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AMG 900

Aurora Kinase inhibitor

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Catalog No. A11066

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
AMG 900 5mg A11066-5
AMG 900 10mg A11066-10
AMG 900 50mg A11066-50
AMG 900 100mg A11066-100
AMG 900 10mM * 1mL in DMSO A11066-10mM-D

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

AMG 900 is a novel potent and highly selective pan-aurora kinase inhibitor with activity in taxane-resistant tumor cell lines.

AMG 900

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Chemical Information

Catalog Num A11066
Actions Inhibitor
M. Wt 503.6
Formula C28H21N7OS
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 945595-80-2
Synonyms AMG-900, AMG900

Biological Activity

AMG 900 is a novel potent and highly selective pan-aurora kinase inhibitor with activity in taxane-resistant tumor cell lines.
Target Value
AuroraCIC50: 1nM
AuroraBIC50: 4nM
AuroraAIC50: 5nM
p38αIC50: 53nM
TYK2IC50: 220nM
JNK2IC50: 520nM
MetIC50: 550nM
Tie-2IC50: 650nM


Solubility (25°C) * In vitro DMSO 100 mg/mL (198.57 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 20 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.86 mL 99.29 mL 198.57mL
0.5 mM 3.97 mL 19.86 mL 39.71 mL
1 mM 1.99 mL 9.93 mL 19.86 mL
5 mM 0.4 mL 1.99 mL 3.97 mL

*The above data is based on the productmolecular weight 503.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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