Total item
Cart Subtotal
$0.00 Biological Activity
AMG 900 is a novel potent and highly selective pan-aurora kinase inhibitor with activity in taxane-resistant tumor cell lines.
Targets
| Target | Value |
|---|---|
| AuroraC | IC50: 1nM |
| AuroraB | IC50: 4nM |
| AuroraA | IC50: 5nM |
| p38α | IC50: 53nM |
| TYK2 | IC50: 220nM |
| JNK2 | IC50: 520nM |
| Met | IC50: 550nM |
| Tie-2 | IC50: 650nM |
| In vitro (25°C) | DMSO | 100 mg/mL (198.57 mM) | |
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
| In vivo | 1% DMSO/30% polyethylene glycol/1% Tween 80 | 20 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.86 mL | 99.29 mL | 198.57 mL |
| 0.5 mM | 3.97 mL | 19.86 mL | 39.71 mL |
| 1 mM | 1.99 mL | 9.93 mL | 19.86 mL |
| 5 mM | 0.4 mL | 1.99 mL | 3.97 mL |
*The above data is based on the productmolecular weight 503.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11066 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 503.6 |
| Formula | C28H21N7OS |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 945595-80-2 |
| Synonyms | AMG-900, AMG900 |
| SMILES | CC1=CSC(=C1)C2=NN=C(C3=CC=CC=C32)NC4=CC=C(C=C4)OC5=C(C=CC=N5)C6=NC(=NC=C6)N |
Product Tags
Product Questions
Product Questions
No Questions
Keywords:buy AMG 900 | AMG 900 Supplier | purchase | cost | manufacturer | order | distributor | buy 945595-80-2| 945595-80-2 Supplier | purchase 945595-80-2 | 945595-80-2 cost | 945595-80-2 manufacturer | order 945595-80-2 | 945595-80-2 distributor
Contact information
United StatesAdooq Bioscience
Toll Free: (866) 930-6790
Fax: +1-323-606-8156
Email: [email protected]
Not your Region? View all Distributors
Adooq Quality Guarantee
We promise all products perform as described.