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ANA-12 is a TrkB receptor antagonist that demonstrates a 2-site mode of action, preventing activation by BDNF non-competitively.
Targets
| TrkB | ||||
| 10 nM(Kd) |
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.54 mL | 122.7 mL | 245.4 mL |
| 0.5 mM | 4.91 mL | 24.54 mL | 49.08 mL |
| 1 mM | 2.45 mL | 12.27 mL | 24.54 mL |
| 5 mM | 0.49 mL | 2.45 mL | 4.91 mL |
*The above data is based on the productmolecular weight 407.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13877 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 407.49 |
| Formula | C22H21N3O3S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 219766-25-3 |
| Synonyms | ANA12, ANA 12 |
| SMILES | O=C(C1=CC2=CC=CC=C2S1)NC3=CC=CC=C3C(NC4C(NCCCC4)=O)=O |
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