ANA-12

Catalog No.: A13877

TrkB inhibitor

ANA-12 Chemical Structure

CAS NO. 219766-25-3

ANA-12 is a TrkB receptor antagonist that demonstrates a 2-site mode of action, preventing activation by BDNF non-competitively.

Availability: In stock

Package Price Qty
10 mg
$110.00
25 mg
$210.00
50 mg
$360.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

ANA-12 is a TrkB receptor antagonist that demonstrates a 2-site mode of action, preventing activation by BDNF non-competitively.
Targets
TrkB
10 nM(Kd)
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.54 mL 122.7 mL 245.4 mL
0.5 mM 4.91 mL 24.54 mL 49.08 mL
1 mM 2.45 mL 12.27 mL 24.54 mL
5 mM 0.49 mL 2.45 mL 4.91 mL

*The above data is based on the productmolecular weight 407.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13877
Actions Inhibitor
M. Wt 407.49
Formula C22H21N3O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 219766-25-3
Synonyms ANA12, ANA 12
SMILES O=C(C1=CC2=CC=CC=C2S1)NC3=CC=CC=C3C(NC4C(NCCCC4)=O)=O

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