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Anacetrapib (MK-0859)

Catalog No.: A11084

CETP inhibitor

Anacetrapib (MK-0859)

Anacetrapib (MK-0859) Chemical Structure

CAS NO. 875446-37-0

Anacetrapib (MK-0859) is a CETP inhibitor being developed to treat hypercholesterolemia (elevated cholesterol levels) and prevent cardiovascular disease.

Availability: In stock

Package Price Qty
5 mg
$120.00
10 mg
$200.00
50 mg
$580.00
100 mg
$880.00
10mM * 1mL in DMSO
$212.00
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Biological Activity

Anacetrapib (MK-0859) is a CETP inhibitor being developed to treat hypercholesterolemia (elevated cholesterol levels) and prevent cardiovascular disease.
In vitro (25°C) DMSO 108 mg/mL (169.41 mM)
Water Insoluble
Ethanol 108 mg/mL (169.41 mM)
In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 9 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.69 mL 78.43 mL 156.86 mL
0.5 mM 3.14 mL 15.69 mL 31.37 mL
1 mM 1.57 mL 7.84 mL 15.69 mL
5 mM 0.31 mL 1.57 mL 3.14 mL

*The above data is based on the productmolecular weight 637.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11084
Actions Inhibitor
CAS No. 875446-37-0
Formula C30H25F10NO3
M. Wt 637.5
Purity >98%
Synonyms MK0859
SMILES C[[email protected]]1[[email protected]](OC(=O)N1CC2=C(C=CC(=C2)C(F)(F)F)C3=CC(=C(C=C3OC)F)C(C)C)C4=CC(=CC(=C4)C(F)(F)F)C(F)(F)F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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