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Catalog No.
Product Name
Application
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Product Citation
TOK-001 (Galeterone) is both an androgen receptor antagonist and CYP17A1 inhibitor.
AR inhibitor downregulator
AZD-3514 is a potent androgen receptor downregulator with potential anticancer cancer activity.
1 publications
Qian Liu, .et al. , Research Square , 2023, Mar 10
CYP17A1/androgen synthesis inhibitor
Orteronel (TAK700) is an androgen synthesis inhibitor. It selectively inhibits the enzyme CYP17A which is expressed in testicular, adrenal, and prostatic tumor tissues.
CSRM617 Hydrochloride is an inhibitor of the transcription factor ONECUT2 (OC2), thereby suppressing metastasis in mice.
androgen receptor/CYP17A1 dual inhibitor
ODM-204 is novel nonsteroidal dual inhibitor of both androgen receptor and CYP17A1 enzyme, with IC50s of 80?nM and 22 nM, respectively.
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