PDGFR

Catalog No.Inhibitor Name PDGFRPDGFRαPDGFRβOther
A10001Sorafenib Tosylate
**
**
Raf-1,VEGFR2/Flk1,B-Raf
A10468Imatinib Mesylate
c-Kit,v-Abl
A10880Sunitinib Malate
****
FLT3,Kit,VEGFR2
A10080Ponatinib
****
Abl,VEGFR2,FGFR1
A10103Axitinib
***
****
VEGFR1/FLT1,VEGFR2/Flk1,VEGFR3
A10259Imatinib
**
c-Kit,v-Abl
A10137Nintedanib
**
**
VEGFR3,VEGFR2,LCK
A10699Pazopanib HCl
**
VEGFR1,VEGFR2,VEGFR3
A11411Dovitinib
*
***
FLT3,c-Kit,FGFR1
A10025Linifanib
**
VEGFR1/FLT1,CSF-1R,FLT3
A11052Crenolanib
****
****
A10558Masitinib
*
*
Kit,Lyn B,Abl1
A10101Tivozanib
***
**
VEGFR2,VEGFR3,EphB2
A10610Amuvatinib
***
c-Kit (D816H),FLT3 (D835Y)
A10608Motesanib Diphosphate
**
VEGFR1,VEGFR2,VEGFR3
A10953Orantinib
***
FGFR1,Flk1
A11350CP-673451
***
****
c-Kit,VEGFR2,VEGFR1
A10502Ki8751
**
VEGFR2,c-Kit,FGFR2
A10903Telatinib
***
c-Kit,VEGFR3,VEGFR2
A11207PP121
****
Hck,VEGFR,mTOR
A11518Pazopanib
**
VEGFR1,VEGFR2,VEGFR3
A10504KRN 633
*
*
VEGFR3,VEGFR2,VEGFR1
A10198Dovitinib Dilactic Acid
*
***
FLT3,c-Kit,VEGFR3/FLT4
A11753MK-2461
***
c-Met (M1250T),c-Met (Y1235D),c-Met (Y1230H)
A14156AZD2932
****
Flt3,VEGFR-2,c-Kit
A15062DCC-2618
***
***
c-Kit

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

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  1. AP24534 (Ponatinib)

    Catalog No. A10080
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    BCR-ABL inhibitor
    AP24534 (Ponatinib) is a potent multi-kinase and pan-BCR-ABL inhibitor. Learn More

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