Arry-380 analog

Catalog No.: A11027

HER2 Inhibitor

Arry-380 analog

Arry-380 analog Chemical Structure

CAS NO. 937265-83-3

ARRY-380 is an ErbB-2 inhibitor that selectively binds to and inhibits the phosphorylation of ErbB-2, resulting in growth inhibition and death of ErbB-2-expressing tumor cells.

Availability: In stock

Package Price Qty
5 mg
$60.00
10 mg
$90.00
50 mg
$240.00
100 mg
$440.00
10mM * 1mL in DMSO
$65.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

ARRY-380 is an ErbB-2 inhibitor that selectively binds to and inhibits the phosphorylation of ErbB-2, resulting in growth inhibition and death of ErbB-2-expressing tumor cells.
In vitro DMSO 114 mg/mL (200.12 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.55 mL 87.73 mL 175.47 mL
0.5 mM 3.51 mL 17.55 mL 35.09 mL
1 mM 1.75 mL 8.77 mL 17.55 mL
5 mM 0.35 mL 1.75 mL 3.51 mL

*The above data is based on the productmolecular weight 569.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11027
Actions Inhibitor
M. Wt 569.9
Formula C29H27N7O4S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 937265-83-3
Synonyms Arry380
SMILES CC1=C(C=CC(=C1)NC2=NC=NC3=C2C=C(C=C3)C4=CC=C(O4)CNCCS(=O)(=O)C)OC5=CC6=NC=NN6C=C5

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