AT-406 (SM-406, ARRY-334543)

Catalog No.: A11163

IAP inhibitor

AT-406 (SM-406, ARRY-334543)

AT-406 (SM-406, ARRY-334543) Chemical Structure

CAS NO. 1071992-99-8

AT-406 is an orally bioavailable inhibitor of IAP family of proteins with potential apoptotic inducing and antineoplastic activity. AT-406 selectively inhibits the biological activity of IAP proteins, including X chromosome-linked IAP (XIAP), the cellular IAPs 1 (c-IAP1) and 2 (c-IAP2) and melanoma inhibitor of apoptosis protein (ML-IAP).

Availability: In stock

Package Price Qty
5 mg
$90.00
10 mg
$160.00
50 mg
$500.00
200 mg
$1,650.00
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Biological Activity

AT-406 is an orally bioavailable inhibitor of IAP family of proteins with potential apoptotic inducing and antineoplastic activity. AT-406 selectively inhibits the biological activity of IAP proteins, including X chromosome-linked IAP (XIAP), the cellular IAPs 1 (c-IAP1) and 2 (c-IAP2) and melanoma inhibitor of apoptosis protein (ML-IAP).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.8 mL 89.01 mL 178.03 mL
0.5 mM 3.56 mL 17.8 mL 35.61 mL
1 mM 1.78 mL 8.9 mL 17.8 mL
5 mM 0.36 mL 1.78 mL 3.56 mL

*The above data is based on the productmolecular weight 561.71. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11163
Actions Inhibitor
M. Wt 561.71
Formula C32H43N5O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1071992-99-8
Synonyms AT406, SM-406, ARRY-334543
SMILES C[[email protected]@H](C(=O)N[[email protected]]1CN(CC[[email protected]]2CC[[email protected]](N2C1=O)C(=O)NC(C3=CC=CC=C3)C4=CC=CC=C4)C(=O)CC(C)C)NC

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