Onalespib (AT13387)

Name: Onalespib (AT13387)
SKU: A11062
Price: 72 USD
Rating: 5 (3 reviews)

Catalog No.: A11062

HSP90 Inhibitor

Adooq's Onalespib (AT13387) has been cited by 3 publications

AT13387 is a targeted inhibitor of Hsp90,inhibiting its chaperone function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival.

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Grouped product items
Product Name	Price	Stock
AT13387 5mg	Special Price $72.00 Regular Price $90.00	In stock
AT13387 10mg	Special Price $120.00 Regular Price $150.00	In stock
AT13387 50mg	Special Price $280.00 Regular Price $350.00	In stock
AT13387 100mg	Special Price $456.00 Regular Price $570.00	In stock
*AT13387 10mM 1mL in DMSO**	Special Price $76.00 Regular Price $95.00	In stock
Bulk Size	Bulk Discount

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Important Notice: For research use only. We do not sell to patients.

Data Sheet

SDS

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Adooq Products cited in reputable paper

Adooq's Onalespib (AT13387) has been cited by 3 publications

Boucherat O, .et al. , Am J Respir Crit Care Med, 2018, Jul 1;198(1):90-103 PMID: 29394093

Olivier Boucherat, .et al. , Sci Rep, 2017, 7: 4546 PMID: 28674407

Hiroki Murano, .et al. , Plant Biotechnol Rep, 2017, 11:107-113

Biological Activity

Discription

AT13387 is a targeted inhibitor of Hsp90,inhibiting its chaperone function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival.

Targets

Target	Value

Product Information

Catalog Num	A11062
Formula	C24H31N3O3
Molecular Weight	409.5
CAS Number	912999-49-6
SMILES	CC(C)C1=C(C=C(C(=C1)C(=O)N2CC3=C(C2)C=C(C=C3)CN4CCN(CC4)C)O)O
Synonyms	AT-13387
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro (25°C)	DMSO	22 mg/mL (53.72 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+30% PEG 300+ddH2O (prepare before use)	9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.42 mL	122.1 mL	244.2 mL
0.5 mM	4.88 mL	24.42 mL	48.84 mL
1 mM	2.44 mL	12.21 mL	24.42 mL
5 mM	0.49 mL	2.44 mL	4.88 mL

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