Onalespib (AT13387)

Catalog No.: A11062

HSP90 Inhibitor

Onalespib (AT13387)

Onalespib (AT13387) Chemical Structure

CAS NO. 912999-49-6

AT13387 is a targeted inhibitor of Hsp90,inhibiting its chaperone function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $90.00

Special Price $81.00

10 mg

Regular Price: $150.00

Special Price $135.00

50 mg

Regular Price: $350.00

Special Price $315.00

100 mg

Regular Price: $570.00

Special Price $513.00

10mM * 1mL in DMSO

Regular Price: $95.00

Special Price $85.50

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

AT13387 is a targeted inhibitor of Hsp90,inhibiting its chaperone function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival.
Targets
HSP90 (Cell-free assay)
18 nM
In vitro (25°C) DMSO 25 mg/mL (61.04 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 15% Captisol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.42 mL 122.1 mL 244.2 mL
0.5 mM 4.88 mL 24.42 mL 48.84 mL
1 mM 2.44 mL 12.21 mL 24.42 mL
5 mM 0.49 mL 2.44 mL 4.88 mL

*The above data is based on the productmolecular weight 409.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11062
Actions Inhibitor
M. Wt 409.5
Formula C24H31N3O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 912999-49-6
Synonyms AT-13387
SMILES CC(C)C1=C(C=C(C(=C1)C(=O)N2CC3=C(C2)C=C(C=C3)CN4CCN(CC4)C)O)O

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