TC-S 7010 (Aurora A Inhibitor I)

Catalog No.: A10100
Aurora A Inhibitor

Aurora A Inhibitor I is a potent and selective inhibitor of Aurora A kinase (AurA), with IC50 values to be 3.4 nM (Aurora A) and unusually high selectivity 1000 fold against Aurora B; a useful tool compound for investigating the cellular role of Aurora A kinases.

Grouped product items
Product Name Price Stock Qty
TC-S 7010 (Aurora A Inhibitor I) 5mg
$60.00
In stock
TC-S 7010 (Aurora A Inhibitor I) 10mg
$110.00
In stock
TC-S 7010 (Aurora A Inhibitor I) 50mg
$380.00
In stock
TC-S 7010 (Aurora A Inhibitor I) 100mg
$600.00
In stock
TC-S 7010 (Aurora A Inhibitor I) 10mM * 1mL in DMSO
$97.00
In stock
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Biological Activity
Discription

Aurora A Inhibitor I is a potent and selective inhibitor of Aurora A kinase (AurA), with IC50 values to be 3.4 nM (Aurora A) and unusually high selectivity 1000 fold against Aurora B; a useful tool compound for investigating the cellular role of Aurora A kinases.

Targets
Target Value
Product Information
Catalog Num A10100
Formula C31H31ClFN7O2
Molecular Weight 588.1
CAS Number 1158838-45-9
SMILES CCN1CCN(CC1)C(=O)CC2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4=CC=C(C=C4)C(=O)NC5=CC=CC=C5Cl)F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 105 mg/mL (178.54 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5%DMSO+40%PEG300+5%Tween80+50%ddH2O 1.18 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17 mL 85.02 mL 170.04 mL
0.5 mM 3.4 mL 17 mL 34.01 mL
1 mM 1.7 mL 8.5 mL 17 mL
5 mM 0.34 mL 1.7 mL 3.4 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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