Catalog No.: A13205

ATR kinase inhibitor


AZ-20 Chemical Structure

CAS NO. 1233339-22-4

AZ20 is a potent and selective inhibitor of ATR with an IC50 value of 5 nM.

Availability: In stock

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5 mg
10 mg
25 mg
50 mg
10mM * 1mL in DMSO
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Biological Activity

AZ20 is a potent and selective inhibitor of ATR with an IC50 value of 5 nM.
ATR (Cell-free assay) mTOR (Cell-free assay)
5 nM38 nM
In vitro DMSO 80 mg/mL (193.93 mM)
Water Insoluble
Ethanol 3 mg/mL (7.27 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.24 mL 121.21 mL 242.42 mL
0.5 mM 4.85 mL 24.24 mL 48.48 mL
1 mM 2.42 mL 12.12 mL 24.24 mL
5 mM 0.48 mL 2.42 mL 4.85 mL

*The above data is based on the productmolecular weight 412.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13205
Actions Inhibitor
CAS No. 1233339-22-4
Formula C21H24N4O3S
M. Wt 412.51
Purity >98%
Synonyms AZ20, AZ 20
SMILES C[[email protected]@H]1COCCN1C2=NC(=NC(=C2)C3(CC3)S(=O)(=O)C)C4=C5C=CNC5=CC=C4

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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