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MEK Inhibitor

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Catalog No. A10115

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
AZD8330 5mg A10115-5
AZD8330 10mg A10115-10
AZD8330 50mg A10115-50
AZD8330 100mg A10115-100
AZD8330 10mM * 1mL in DMSO A10115-10mM-D

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

AZD8330 is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 nM. Phase 1.


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Chemical Information

Catalog Num A10115
Actions Inhibitor
M. Wt 461.2
Formula C16H17FIN3O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 869357-68-6
Synonyms AZD-8330

Biological Activity

AZD8330 is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 nM. Phase 1.
ERK phosphorylation MEK1/2
0.4 nM7 nM


Solubility (25°C) * In vitro DMSO 92 mg/mL (199.46 mM)
Water <1 mg/mL (<1 mM)
Ethanol 92 mg/mL (199.46 mM)
In vivo 0.5% hydroxyethyl cellulose/0.1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.68 mL 108.41 mL 216.83mL
0.5 mM 4.34 mL 21.68 mL 43.37 mL
1 mM 2.17 mL 10.84 mL 21.68 mL
5 mM 0.43 mL 2.17 mL 4.34 mL

*The above data is based on the productmolecular weight 461.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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