2018-2019 AdooQ Catalog Book Available Click here to download

World Leading Inhibitor Supplier

France
  • Toll Free 866-930-6790
Trusted by 10,000+ Scientists since 2006

AZD8330

MEK Inhibitor

0 Customer Reviews
Catalog No. A10115

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
AZD8330 5mg A10115-5
€104.50
AZD8330 10mg A10115-10
€190.00
AZD8330 50mg A10115-50
€589.00
AZD8330 100mg A10115-100
€1,026.00
AZD8330 10mM * 1mL in DMSO A10115-10mM-D
€152.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

AZD8330 is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 nM. Phase 1.

AZD8330

Double click on above image to view full picture

Zoom Out
Zoom In

More Views

Publications citing Adooq Products

Chemical Information

Catalog Num A10115
Actions Inhibitor
M. Wt 461.2
Formula C16H17FIN3O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 869357-68-6
Synonyms AZD-8330
SMILES code CC1=CC(=C(N(C1=O)C)NC2=C(C=C(C=C2)I)F)C(=O)NOCCO
Chemical Name 2-(2-Fluoro-4-iodophenylamino)-N-(2-hydroxyethoxy)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxamide

Biological Activity

Description
 AZD8330 is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 nM. Phase 1.
Targets
ERK phosphorylation MEK1/2
0.4 nM7 nM

Solubility

Solubility (25°C) * In vitro DMSO 92 mg/mL (199.46 mM)
Water <1 mg/mL (<1 mM)
Ethanol 92 mg/mL (199.46 mM)
In vivo 0.5% hydroxyethyl cellulose/0.1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.68 mL 108.41 mL 216.83mL
0.5 mM 4.34 mL 21.68 mL 43.37 mL
1 mM 2.17 mL 10.84 mL 21.68 mL
5 mM 0.43 mL 2.17 mL 4.34 mL

*The above data is based on the productmolecular weight 461.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

View Related Products By Research Topics

Ordering online

To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.

To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.

When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards.  We will then liaise with you or your purchasing department to confirm the order.

Found your products but not ready to order?

Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.

Ordering offline

You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order.  Our contact details are:

We require the following information to process your order:
  • The catalog number for each product. 
  • Your email address or fax number. 
  • Your name and telephone number. 
  • Shipping address and billing address.
  • Purchase order numbers.

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Be the first to review this product

Similar product(s)


Keywords:buy AZD8330 | AZD8330 Supplier | purchase AZD8330 | AZD8330 cost | AZD8330 manufacturer | order AZD8330 | AZD8330 distributor | buy 869357-68-6| 869357-68-6 Supplier | purchase 869357-68-6 | 869357-68-6 cost | 869357-68-6 manufacturer | order 869357-68-6 | 869357-68-6 distributor

Receive our newsletter

To keep up to date with the latest products, news from us. We only send a few emails a year and you can unsubscribe at any time.

We Using Safe Payments:
© 2006-2018 AdooQ BioScience. All Rights Reserved.