AZD8931 (Sapitinib)

Catalog No.: A10116
pan-EGFR/pan-erbB inhibitor
AZD8931 is an oral, equipotent inhibitor of ErbB1, ErbB2 and ErbB3 receptor signaling.
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AZD8931 5mg
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AZD8931 10mg
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AZD8931 25mg
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AZD8931 100mg
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AZD8931 10mM * 1mL in DMSO
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's AZD8931 (Sapitinib) has been cited by 1 publications
  • Takeshi Ito, .et al. , Biochem Biophys Res Commun, 2019, in Press
  • Biological Activity
    Discription AZD8931 is an oral, equipotent inhibitor of ErbB1, ErbB2 and ErbB3 receptor signaling.
    Target Value
    Product Information
    Catalog Num A10116
    Formula C23H25ClFN5O3
    Molecular Weight 473.9
    CAS Number 848942-61-0
    Synonyms Momelotinib

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    In vitro (25°C) DMSO 37 mg/mL (78.07 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 21.1 mL 105.51 mL 211.01 mL
    0.5 mM 4.22 mL 21.1 mL 42.2 mL
    1 mM 2.11 mL 10.55 mL 21.1 mL
    5 mM 0.42 mL 2.11 mL 4.22 mL
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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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